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Latest Knockout rat Stories

2014-05-27 23:06:48

Findings to Enhance System That Is Transforming Genetic Research Charlottesville, VA (PRWEB) May 27, 2014 Researchers at the University of Virginia School of Medicine have devised a way to detect unintended side effects of manipulating genes using a revolutionary new system that is sweeping the scientific world by storm. The gene targeting system, called CRISPR, allows editing of genetic information at specifically targeted sites in the genome. UVA’s new approach reveals the system has...

Two Human Proteins Found To Affect How 'Jumping Gene' Gets Around
2013-11-21 13:55:24

Johns Hopkins Medicine Using a new method to catch elusive "jumping genes" in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place. The discovery, described in the Nov. 21 issue of Cell, breaks new ground, they say, in understanding the arms race between a jumping gene driven to colonize new areas of the human genome and cells working to limit the risk posed by such volatile bits of DNA. Jumping genes, more...

2011-05-11 12:00:00

LEXINGTON, Ky., and MOUNTAIN VIEW, Calif., May 11, 2011 /PRNewswire/ -- Transposagen Biopharmaceuticals, Inc. (Transposagen) and System Biosciences (SBI), both leaders in genetic modification technology, have announced a non-exclusive marketing and distribution agreement between the two biotechnology companies involving Transposagen's piggyBac(TM) technology. The piggyBac(TM) Genetic Modification System enables researchers to: Alter the genomes of numerous animal species with a simple...

2011-03-17 07:00:00

ST. LOUIS, March 17, 2011 /PRNewswire/ -- Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq: SIAL), announced that its SAGE Labs initiative has created a suite of knockout rat models of Parkinson's disease in collaboration with The Michael J. Fox Foundation for Parkinson's Research (MJFF). Developed using the proprietary SAGEspeed(TM) model creation process, these off-the-shelf rat models represent a...

2011-01-05 09:00:00

LEXINGTON, Ky., Jan. 5, 2011 /PRNewswire/ -- Transposagen Biopharmaceuticals, Inc. (Transposagen), a leader in genetic modification technology, announced today that it has entered into a non-exclusive license agreement with Cellular Dynamics International (CDI), the world's largest producer of human induced pluripotent stem (iPS) cell lines and tissue cells for drug discovery and safety. The license agreement allows CDI to use Transposagen's piggyBac technology in the creation of its...

2010-10-13 13:39:00

LEXINGTON, Ky., Oct. 13 /PRNewswire/ -- Transposagen Biopharmaceuticals, Inc. (Transposagen), the worldwide leader in genetically modified rats, has announced today that it has entered into an exclusive marketing and distribution agreement with Charles River Laboratories, a leading global provider of research models and services. The license includes two of Transposagen's high-value TGEM(TM) Knockout Rat Models, one rat line contains a mutation in the p53 gene, the most studied tumor...

2010-05-28 13:35:39

For two decades, the laboratory mouse has been the workhorse of biomedical studies and the only mammal whose genes scientists could effectively and reliably manipulate to study human diseases and conditions. Now researchers at UT Southwestern Medical Center have added another experimental research animal to the scientific stable: the rat. In a new study appearing in the June issue of Nature Methods, UT Southwestern researchers detail how they created 35 new rat "lines," with each type of...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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