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Latest La Jolla Institute Stories

2013-06-24 19:38:34

Nature-published study reveals previously unknown role of septin proteins A major study from researchers at the La Jolla Institute for Allergy and Immunology provides new revelations about the intricate pathways involved in turning on T cells, the body's most important disease-fighting cells, and was published today in the prestigious scientific journal Nature. The La Jolla Institute team is the first to prove that a certain type of protein, called septins, play a critical role in...

2013-04-15 13:41:37

New data on T cells' protective role suggests need for new approach to dengue vaccine design As efforts to create a strong and effective vaccine for the dreaded dengue virus continue to hit snags, a new study from researchers at the La Jolla Institute for Allergy & Immunology offers surprising evidence that suggests the need for a revamped approach to dengue vaccine design. The finding runs counter to current scientific understanding of the key cells that need to be induced to develop...

2013-03-13 17:52:05

La Jolla Institute and Cardiff University discovery aids efforts toward cytomegalovirus vaccine A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage. But efforts to develop a first-ever CMV vaccine are gaining...

2012-08-15 01:02:20

Researcher finds autoimmune response contributes to inflammation in the artery wall Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system. A number of research studies have demonstrated inflammation's role in fueling plaque buildup, also...

2012-05-29 08:12:26

Researchers identify mechanism key in drug allergy Adverse drug reactions are a major issue that cause harm, are costly and restrict treatment options for patients and the development of new drugs. A groundbreaking finding by researchers from the La Jolla Institute for Allergy & Immunology could lead to a new way to dramatically improve drug safety by identifying drugs at risk to cause potentially fatal genetic-linked hypersensitivity reactions before their use in man....

2012-01-12 14:39:04

JDRF's organ donation network key in research findings Researchers at the La Jolla Institute for Allergy & Immunology have proven — for the first time in human tissues -- the specific immune system T cells which trigger the destruction of type 1 diabetes in the pancreas. The finding is an important advance that verifies in humans several important disease characteristics shown in mouse studies and provides a key focal point for interrupting the disease process. "This study...

2011-12-02 01:52:22

Discovery provides new insights on role of histamine releasing factor in asthma and allergies La Jolla Institute for Allergy & Immunology scientists have identified the histamine releasing factor (HRF) molecule as a promising target for developing new treatments for a number of allergic reactions including asthma. The research team, led by Toshiaki Kawakami, M.D., Ph.D., is also the first to clarify the role of the HRF molecule in promoting asthma and some allergies, including...

2011-12-02 01:47:29

Cellular movies could greatly enhance search for Type 1 disease interventions A war is being waged in the pancreases of millions of people throughout the world. The siege leads to the development of type 1 diabetes and has been a battlefield largely hidden from view-- until now. Researchers at the La Jolla Institute for Allergy & Immunology have created the first cellular movies showing the destruction underlying type 1 diabetes in real-time in mouse models. This detailed, dynamic view...

2011-10-03 19:57:29

Discovery could lead to new and better vaccines for Listeria, HIV and other pathogens Researchers at the La Jolla Institute for Allergy & Immunology have identified a previously unknown mechanism that generates protective immune memory cells to fight recurring infections at the body's mucosal linings — which include the mouth, the intestines, the lungs and other areas. These are the main entry points for many viruses and other infectious organisms. The findings were published...

2011-10-03 15:43:51

Discovery opens up novel therapeutic avenue for autoimmune diseases Most of the time, the immune system is the body's protector, warding off invading viruses and bacteria before they can lead to infection and disease. But in autoimmune diseases, the immune system does an about face, turning on the body and attacking normal cells. A major discovery by La Jolla Institute scientist Amnon Altman, Ph.D., and his colleagues, of a previously unknown molecular interaction that is essential for...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
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