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Latest Lamotrigine Stories

2008-11-12 12:00:15

GlaxoSmithKline has announced that it will close its manufacturing site in Dartford. Following the conclusion of a recent review of activities at its manufacturing site in Dartford, the company proposes to close the facility and transfer production to alternative facilities. The proposed closure, which is subject to consultation with trade union and staff representatives, would result in the loss of around 620 established roles at the Dartford site over the next four years, with closure of...

2008-08-11 12:01:13

WALTHAM, Mass., Aug. 11 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that an astonishing 52.3 percent of newly diagnosed bipolar disorder patients are prescribed antidepressant drugs first line. The new report entitled Treatment Algorithms in Bipolar Disorder finds that this high preponderance of early-line antidepressant use stems from primary care physician prescribing. Surveyed primary...

2008-08-01 12:01:08

Lupin Pharmaceuticals has received final approval for its abbreviated new drug application for divalproex sodium delayed-release tablets, 125mg, 250mg and 500mg from the FDA. Commercial shipments of the product have already commenced. Lupin's divalproex sodium delayed-release tablets are the AB-rated generic equivalent of Abbott Laboratories's Depakote tablets, indicated for the treatment of certain types of seizures and convulsions. It may be prescribed alone or with other epilepsy...

2008-07-09 06:00:38

The FDA is close to adding a black box warning to epilepsy drugs after a safety review showed that they increase patients' risk of suicidal thoughts and behavior. Datamonitor believes that, rather than impacting sales of such drugs for the treatment of epilepsy, the warning will represent a greater threat to sales of these drugs for indications where alternative drug classes are available. The FDA has analyzed data from 199 placebo-controlled trials of 11 epilepsy drugs involving a total of...

2006-08-07 16:57:39

By Anthony J. Brown, MD NEW YORK (Reuters Health) - Roughly 20 percent of epileptic women who take the antiseizure drug valproate during pregnancy will have a fetus with a serious adverse outcome, almost twice the rate associated with the next most problematic antiepileptic drug, new research shows. Several years ago, the American Academy of Neurology and other groups issued guidelines for treating epileptic women during pregnancy. Since antiepileptic drugs, in general, have been...

2006-03-30 08:35:00

By Toni Clarke BOSTON -- Cephalon Inc.'s experimental drug to treat attention deficit hyperactivity disorder may have fallen victim more to the timing of its audition than the quality of its performance, some experts say. Last week, a panel of advisers to the U.S. Food and Drug Administration voted 12 to 1 against approving the drug, Sparlon, amid concern it might cause a potentially fatal skin allergy called Stevens Johnson Syndrome. In a 950-person trial, one patient developed a blistering...

2005-10-04 14:48:15

Landover, MD (October 4, 2005) "“ Today, the Epilepsy Foundation issued a Call to Action to women of childbearing age who take anticonvulsant medications for conditions that include epilepsy, migraine headaches, and certain psychiatric disorders, urging them to talk to their healthcare providers about treatment options. The Call to Action was created in cooperation with medical experts and representatives from leading medical professional and voluntary health organizations....

2005-07-11 12:28:13

By Richard Woodman LONDON (Reuters Health) - Drug maker GlaxoSmithKline has issued a "Dear Doctor" letter advising that its anti-epilepsy drug Lamictal (lamotrigine) can reduce the effectiveness of oral contraceptives. New data have demonstrated an interaction between combined oral contraceptives and lamotrigine which could lead to reduced effectiveness of hormonal contraceptives, a revised product label states. "Women should have a review of their contraception when starting lamotrigine,...


Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin