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Latest Lentivirus Stories

2013-07-22 13:07:16

A recent study published in the Neural Regeneration Research (Vol. 8, No. 17, 2013) injected recombinant lentivirus carrying enhanced green fluorescent protein and the target gene Atoh1 into the cochlea of normal rats using a postauricular approach via the round window membrane. After 30 days, recombinant lentivirus was shown to have no impact on the hair cell numbers and auditory functions, infect hair and supporting cells, and promote supporting cells to transdifferentiate into hair cells....

2012-01-26 12:00:11

Using a combination of evolutionary biology and virology, scientists at Fred Hutchinson Cancer Research Center have traced the birth of the ability of some HIV-related viruses to defeat a newly discovered cellular-defense system in primates. The research, led by Michael Emerman, Ph.D., a member of the Hutchinson Center's Human Biology and Basic Sciences Division, and Harmit Malik, Ph.D., a member of the Center's Basic Sciences Division, was published online Jan. 26 ahead of the Feb. 16...

2011-10-03 15:24:35

In a paper published in the October 2011 issue of Experimental Biology and Medicine, a team of researchers at Columbia University Medical Center led by Stephen Tsang, MD, Ph.D have achieved temporary functional preservation of photoreceptors in a mouse model for retinitis pigmentosa (RP) using novel bipartite gene therapy. RP is a heterogeneous disorder characterized by progressive degeneration of rod photoreceptors (which mediate night vision) causing night blindness and eventually total...

Image 1 - Glowing Green Cats Could Be Key In Battle Against AIDS
2011-09-12 05:07:35

  Could glowing, fluorescent green cats be the next great weapon in the fight against AIDS and the HIV virus? Researchers at the Mayo Clinic seem to think so. Researchers at the clinic reported on Sunday that they have developed "a genome-based immunization strategy to fight feline AIDS and illuminate ways to combat human HIV/AIDS and other diseases. The goal is to create cats with intrinsic immunity to the feline AIDS virus." The feline equivalent of HIV, known as feline...

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2011-08-09 07:30:00

Using a virus to kill a virus In what represents an important step toward curing HIV, a USC scientist has created a virus that hunts down HIV-infected cells. Dr. Pin Wang's lentiviral vector latches onto HIV-infected cells, flagging them with what is called "suicide gene therapy" "” allowing drugs to later target and destroy them. "If you deplete all of the HIV-infected cells, you can at least partially solve the problem," said Wang, chemical engineering professor with the USC Viterbi...

2011-02-27 00:01:42

In its continuing support of the DECIPHER Project"”an open access platform for genome-wide RNAi screening and analysis, Cellecta released the 3rd DECIPHER shRNA Expression Library Module which targets an additional 5,000 human genes enabling researchers to now analyze the functionality of over 15,000 human genes for various biological processes with all three human modules. Mountain View, CA (PRWEB) February 25, 2011 Today, Cellecta, Inc. released the 3rd Module of the DECIPHER...

2011-02-14 14:51:38

A method for interfering with disease genes in experimental animals will enhance drug discovery for cancer and other disorders, said a Baylor College of Medicine researcher. A new system called lentiviral pINDUCER enables researchers to turn a gene on or off whenever they want, said Dr. Thomas F. Westbrook, assistant professor of biochemistry and molecular biology, molecular and human genetics and pediatrics at BCM. "This allows us to test any gene in the genome for its role in disease in...

2011-01-25 16:04:50

Give caffeine to cells engineered to produce viruses used for gene therapy and the cells can generate 3- to 8-times more virus, according to a paper published in Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The paper is available free online at www.liebertpub.com/hum This simple and inexpensive strategy for increasing lentivirus production was developed by Brian Ellis, Patrick Ryan Potts, and Matthew Porteus, University of Texas...

2010-11-03 13:02:00

GAITHERSBURG, Md., Nov. 3, 2010 /PRNewswire/ -- Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery products, announced today that it will receive $1,235,306 in cash grants from the U.S. Government under the Patient Protection and Affordable Care Act. Only companies with no more than 250 employees were eligible. Qualifying projects had to show reasonable potential to result in new therapies to treat areas of unmet...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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