Latest Leptin and bone Stories

2011-07-14 07:14:44

(Ivanhoe Newswire)--For some time scientists have known the hormone leptin has acted in the brain to prevent obesity, but the mystery remains as to whether or not this is a natural weight loss treatment. Leptin has been described as our starvation hormone. It tells your brain when you have stored enough energy in your fat cells to engage in normal metabolic processes. Senior study author Dr. Bradford B. Lowell from Beth Israel Deaconess Medical Center and Harvard Medical School was quoted...

2010-01-05 20:53:48

Researchers have found that even a very little bit of the fat hormone leptin goes a long way when it comes to correcting diabetes. The hormone controls the activity of a gene known as IGFBP2 in the liver, which has antidiabetic effects in animals and could have similar therapeutic effect in humans, according to a report published by Cell Press in the January issue of Cell Metabolism. The new findings confirm what some at least had already suspected: that leptin's antidiabetic effects are...

2009-09-03 15:52:31

Leptin-serotonin pathway offers new clues for obesity and osteoporosis prevention New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual. The research, which explains how leptin "“ well-known appetite-suppressing hormone "“ acts in the brain, is published in the Sept. 4 issue of Cell. When the leptin-serotonin pathway is turned on in mice, the...

2009-01-07 18:37:32

The potential of the appetite suppressing hormone -- leptin -- may be realized after all, U.S. researchers say. The discovery of leptin, an appetite-suppressing hormone secreted by fat tissue, created great hopes for an effective treatment for obesity, but it was found the obese are unresponsive to leptin due to leptin resistance in the brain. The study, published in Cell Metabolism, found two chaperones -- 4-PBA or TUDCA -- increase leptin sensitivity as much as 10-fold and resulted in...

2006-07-25 13:25:34

NEW YORK (Reuters Health) - Similar to what has been shown in young adults, fat tissue appears to stimulate bone growth in children who have yet to enter puberty, British researchers report. After puberty, this effect is weakened. In a study reported in The Journal of Clinical Endocrinology and Metabolism, the fat mass in children was an independent predictor of bone mass and size as well as increases in these parameters over the next 2 years. There were some reasons to believe that...

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