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Last updated on April 16, 2014 at 17:34 EDT

Latest Lewy body Stories

2014-03-10 12:26:00

LBD, the Second Most Common Progressive Dementia after Alzheimer's ATLANTA, March 10, 2014 /PRNewswire-USNewswire/ -- Today, for Brain Awareness Week, March 10-16, 2014, the Lewy Body Dementia Association (LBDA), calls attention to critical differences in dementia-causing disorders that may have potentially life-saving implications. Lewy body dementia (LBD) is the most misdiagnosed form of dementia and, following Alzheimer's disease, is the second most common cause of progressive...

2013-11-07 16:30:26

NEW YORK, Nov. 7, 2013 /PRNewswire-USNewswire/ -- The pursuit of an imaging tool to visualize the protein alpha-synuclein, the hallmark pathology of Parkinson's disease (PD), in the brain is the subject of a paper published today in the Journal of Parkinson's Disease by three researchers from The Michael J. Fox Foundation for Parkinson's Research (MJFF). The Foundation has assembled and leads a consortium to develop a radioactive PET tracer that could lead to better therapies and...

2013-05-10 11:57:50

Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan a clinical trial in humans to study the effects. They say their study, published online May 10 in Human Molecular Genetics, offers a unique and exciting strategy to treat neurodegenerative diseases that feature abnormal buildup of proteins in Parkinson's disease,...

2013-04-08 12:16:35

Research presented at the Genetics Society of America's ongoing annual Drosophila Conference in Washington, D.C., suggests that mannitol, a sugar substitute, could lead to a future treatment for Parkinson's disease Researchers from Tel Aviv University describe experiments that could lead to a new approach for treating Parkinson's disease (PD) using a common sweetener, mannitol. This research is presented today at the Genetics Society of America's 54th Annual Drosophila Research Conference...

2012-11-16 11:06:17

Transmission model shows two main hallmarks of Parkinson´s disease - death of dopamine neurons and disease protein clumps Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. Now, after several years of incremental study, researchers at the Perelman School of Medicine, University of Pennsylvania have been able to piece together...

2012-10-22 22:39:08

Analysis of specific biomarkers in a cerebrospinal fluid sample can differentiate patients with Alzheimer's disease from those with other types of dementia. The method, which is being studied by researchers at Sahlgrenska Academy, may eventually permit earlier detection of Alzheimer's disease. Due to the similarity of the symptoms, differentiating patients with Alzheimer's from those with other types of dementia — or patients with Parkinsondisease from those with other motor...

2012-05-16 00:59:30

Two studies by neurological researchers at Rush University Medical Center suggest that, in the future, colonic tissue obtained during either colonoscopy or flexible sigmoidoscopy may be used to predict who will develop Parkinson's disease, a neurodegenerative disorder of aging that that leads to progressive deterioration of motor function due to loss of neurons in the brain that produce dopamine, a neurotransmitter essential to executing movement. Currently, Parkinson's disease afflicts...

2011-10-05 19:11:29

New research suggests that small "seed" amounts of diseased brain proteins can be taken up by healthy neurons and propagated within them to cause neurodegeneration. The research, published by Cell Press in the October 6 issue of the journal Neuron, sheds light on the mechanisms associated with Parkinson's disease (PD) and provides a model for discovering early intervention therapeutics that can prevent or slow the devastating loss of neurons that underlies PD. Alpha-synuclein...

2011-08-15 12:16:27

Shape of key protein surprises researchers A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach. "Our data show that alpha-synuclein was essentially mistakenly characterized as a natively unfolded protein that lacked structure," said Dennis Selkoe, the...

2011-07-12 12:31:00

A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology (www.jcb.org). Insoluble protein clusters are the hallmarks of several neurodegenerative diseases. In PD, neurons harbor insoluble clumps of the protein alpha-synuclein. What triggers these protein pileups remains obscure. A possible clue for PD came when researchers overexpressed alpha-synuclein in human...