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Last updated on April 24, 2014 at 1:21 EDT

Latest Lewy body Stories

2010-04-23 10:44:00

NEW YORK, April 23 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research today announced more than $3 million in previously unannounced awards ending the first quarter of 2010. The funded projects complement the Foundation's annually occurring Pipeline Programs and Critical Challenges in Parkinson's Disease initiatives, which aim to accelerate PD therapeutic development. Many of the 17 different projects announced today provide additional funding to advance...

2010-03-02 14:15:00

NEW YORK, March 2 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research announced up to $5.75 million in total funding available under its three 2010 Critical Challenges. Each year the Foundation tailors specific Challenges to advance one or more of its key research priorities in PD drug development: forging new strategies to define Parkinson's disease and its progression, alter disease course, reduce symptoms and complications of treatment to increase quality...

2010-01-19 11:57:22

Cognitive fluctuations, or episodes when train of thought temporarily is lost, are more likely to occur in older persons who are developing Alzheimer's disease than in their healthy peers, according to scientists at Washington University School of Medicine in St. Louis. Cognitive fluctuations include excessive daytime sleepiness, staring into space and disorganized or illogical thinking. "If you have these lapses, they don't by themselves mean that you have Alzheimer's," says senior author...

2009-12-28 16:59:32

FINDINGS: Several structurally similar small molecules appear capable of protecting cells from alpha-synuclein toxicity, a hallmark of Parkinson's disease. RELEVANCE: Parkinson's disease is a neurodegenerative disorder characterized by tremors, muscle rigidity, and slowed movements. There is currently no cure for the disease, and current Parkinson's therapies only address disease symptoms, not the disease's cellular cause. Small molecules found to protect cells in multiple models of...

2009-12-15 13:00:00

NEW YORK, Dec. 15 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation announced $1.7 million in funding to drive new and continuing Parkinson's research projects at the Banner Sun Health Research Institute and Mayo Clinic Arizona, sites of the Arizona Parkinson's Disease Consortium. Of the total funding, $1.1 million represents renewed funding for directed projects led by principal investigators Charles Adler, MD, PhD, at Mayo Clinic Arizona and Thomas Beach, MD, PhD, at Banner Sun...

2009-10-13 10:47:19

Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. Previous studies have indicated that phosphorylation of alpha-synuclein at amino acid 129 (Ser129) is a key event in alpha-synuclein"“mediated nerve cell toxicity. However, Mel Feany and colleagues, at Brigham and Women's Hospital, Boston, have now identified a counterbalancing role in nerve cell protection for phosphorylation of alpha-synuclein amino acid 125 (Tyr125). In the...

2009-09-08 12:52:00

NEW YORK, Sept. 8 /PRNewswire-USNewswire/ -- The Alzheimer's Drug Discovery Foundation (ADDF) and the Lewy Body Dementia Association (LBDA) invite scientists from the biotechnology industry and academia worldwide to apply for a new collaborative research grant award entitled Lewy Body Dementia Biomarker Research Award. The goal of the program is to catalyze the discovery of innovative biomarkers that aid in early diagnosis, detection and disease monitoring of Lewy body dementias. Lewy...

2009-07-28 09:00:00

Accumulation of the synaptic protein alpha-synuclein, resulting in the formation of aggregates called Lewy bodies in the brain, is a hallmark of Parkinson's and other related neurodegenerative diseases. This pathology appears to spread throughout the brain as the disease progresses. Now, researchers at the University of California, San Diego School of Medicine and Konkuk University in Seoul, South Korea, have described how this mechanism works. Their findings "“ the first to show...

2009-07-11 23:39:41

Mayo Clinic researchers plan to present a study on new techniques to diagnose dementia at a conference in Vienna, the clinic announced Saturday. Researchers developed a framework for using an MRI to create a differential diagnosis of three common neurodegenerative disorders. They will present at the Alzheimer's Association International Conference on Alzheimer's Disease July 11. Their study created a framework for using a structural MRI to diagnose Alzheimer's disease, frontotemporal lobar...

2009-02-26 13:45:00

KIRKLAND, Wash., Feb 26 /PRNewswire/ -- ProteoTech Inc. announced today that it has been awarded a grant from The Michael J. Fox Foundation for Parkinson's Disease Research. In collaboration with Avid Radiopharmaceuticals Inc. (Philadelphia, PA), ProteoTech scientists will utilize ProteoTech's small molecule platform drug technology to develop new imaging agents that will allow doctors to use PET imaging to identify and determine the extent of alpha-synuclein accumulation in the living human...