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Latest Limulus amebocyte lysate Stories

Horseshoe Crab Behavior Impacted By Biomedical Bleeding
2014-02-26 06:56:44

University of New Hampshire DURHAM, N.H. – New research from Plymouth State University and the University of New Hampshire indicates that collecting and bleeding horseshoe crabs for biomedical purposes causes short-term changes in their behavior and physiology that could exacerbate the crabs’ population decline in parts of the east coast. Each year, the U.S. biomedical industry harvests the blue blood from almost half a million living horseshoe crabs for use in pharmaceuticals —...

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2011-05-20 09:20:58

Liquid crystal droplets could replace horseshoe crab blood in common endotoxin test The Food and Drug Administration requires every drug they certify to be tested for certain poisons that damage patient health. The current gold standard for this is the limulus amoebocyte lysate (LAL) assay that involves using the blood of horseshoe crabs, which strangely enough is blue, to test for endotoxin, a substance commonly associated with many symptoms caused by bacterial infections. But researchers at...

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2010-10-20 08:55:54

Sensor uses frog peptides to test for drug and medical device contamination Princeton engineers have developed a sensor that may revolutionize how drugs and medical devices are tested for contamination, and in the process also help ensure the survival of two species of threatened animals. To be fair, some of the credit goes to an African frog. In the wild, the African clawed frog produces antibacterial peptides -- small chains of amino acids -- on its skin to protect it from infection....


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'