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Latest linezolid Stories

2008-11-03 09:00:40

WALTHAM, Mass., Nov. 3 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the Medicare Hospital-Acquired Conditions Initiative will have a significant impact on antibiotic prescribing and infection control practices for hospital-acquired infections. The new Physician & Payer Forum report Hospital Anti-Infectives: Insights on the Impact of Medicare Reforms, Formulary Inclusion, and Uptake of Novel...

2008-10-30 06:00:44

Concert Pharmaceuticals, a biotechnology company, has announced encouraging findings from a preclinical study suggesting that C-20081, a novel, deuterium-containing oxazolidinone antibiotic, may be suitable for once-daily oral and intravenous dosing. In the preclinical study, C-20081 had a 43% increase in plasma half-life compared to linezolid, which might allow for lower overall drug exposure and improved tolerability with a once-daily dose. Concert has evaluated the effect of selective...

2008-10-28 06:00:28

Paratek Pharmaceuticals, a developer of therapeutics for treating bacterial infections, has announced positive Phase II data of the company's lead antibiotic, PTK 0796, a first-in-class aminomethylcycline. The Phase II study compared safety and efficacy of oral and intravenous forms of PTK 0796 to Zyvox in the treatment of patients with complicated skin and skin structure infections (cSSSIs). Paratek's trial met its primary safety and tolerability endpoint, demonstrating no differences...

2008-10-27 12:00:29

Rib-X Pharmaceuticals, a developer of antibiotics for the treatment of antibiotic-resistant infections, has announced positive results from a Phase II clinical trial with the oral form of its compound, radezolid, for the treatment of uncomplicated skin and skin structure infections. The open-label trial met both its primary (efficacy) and secondary (safety) endpoints. All doses of radezolid were as efficacious as linezolid and demonstrated a good safety profile. The study also showed...

2008-10-27 09:00:41

Concert Pharmaceuticals, Inc. today announced findings from a preclinical study suggesting that C-20081, a novel, deuterium-containing oxazolidinone antibiotic, may be suitable for once-daily oral and intravenous dosing. In the preclinical study, C-20081 had a 43% increase in plasma half-life compared to linezolid, which might allow for lower overall drug exposure and improved tolerability with a once-daily dose. These findings were presented in a poster presentation at the 48th Annual...

2008-10-27 09:00:41

WASHINGTON, Oct. 27, 2008 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. presented a detailed analysis of CANVAS I, a globally conducted, multi-center, Phase III clinical trial, at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy / Infectious Diseases Society of America 46th Annual Meeting (ICAAC / IDSA) in Washington, DC. The results of this 702 patient study demonstrated that ceftaroline monotherapy achieved its primary endpoint of non-inferiority...

fa47caadba9878170f61f55fb03e57c11
2008-10-27 07:40:00

Two new forms of experimental drugs may battle a dangerous form of evolving infection, according to researchers. The health condition is called methicillin-resistant Staphylococcus aureus or MRSA.Doctors want the necessary tools to fight the so-called superbug infection.MRSA kills an estimated 19,000 people a year in the United States.The previous treatment, Pfizer Inc's Zyvox, has side effects and MRSA bacteria are already beginning to adapt by what is known as resistance.Paratek...

2008-10-26 12:00:20

Targanta Therapeutics Corporation (NASDAQ: TARG) today announced the presentation of key clinical findings of its lead antibiotic drug candidate, oritavancin, at the combined annual meetings of the 48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the 46th Infectious Disease Society of America (IDSA), taking place in Washington, DC. The presentations highlight the efficacy and safety results of two Phase 3 clinical studies of oritavancin. Sunday, October...

2008-10-26 12:00:10

BOSTON, Oct. 26 /PRNewswire/ -- Paratek Pharmaceuticals, Inc. today announced positive Phase 2 data for the Company's lead antibiotic, PTK 0796, a first-in-class aminomethylcycline (AMC). The Phase 2 study compared safety and efficacy of oral and intravenous (IV) forms of PTK 0796 to Zyvox(R) in the treatment of patients with complicated skin and skin structure infections (cSSSIs). Paratek's trial met its primary safety and tolerability endpoint, demonstrating no differences between PTK...

2008-10-26 12:00:10

REINACH, Switzerland, Oct. 26 /PRNewswire-FirstCall/ -- Arpida today presented the combined results from two pivotal Phase III clinical trials at the 48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, DC. In these studies, intravenous iclaprim, a novel antibiotic, showed high clinical cure rates which were similar to those of the comparator drug, linezolid, in the treatment of...


Latest linezolid Reference Libraries

0_4d46cc72a490344d44ba78359f528175
2011-04-26 21:07:20

Enterococcus is a Gram-positive, commensal bacterium inhabiting the gastrointestinal tracts of humans and other mammals. It is a main constituent of some probiotic food supplements. E. faecalis can cause life-threatening infections in humans, especially in the nosocomial environment, where the naturally high levels of antibiotic resistance found in E. faecalis contribute to its pathogenicity. It is frequently found in root canal-treated teeth in prevalence values ranging from 30% to 90% of...

0_71ad70ea6f0948a7e84406e760c7f5a4
2011-04-15 14:36:05

Enterococcus faecalis "“ formerly classified as part of the Group D Streptococcus system "“ is a Gram-positive, commensal bacterium inhabiting the gastrointestinal tracts of humans and other mammals. It is one of the main constituents of some probiotic food supplements. E. faecalis can cause life-threatening infections in humans. It is frequently found in root canal-treated teeth in prevalence values ranging from 30% to 90% of the cases. It is a non-motile, facultatively anaerobic...

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Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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