Quantcast
Last updated on April 20, 2014 at 21:20 EDT

Latest Lipid signaling Stories

2014-02-14 11:09:28

A protein that has been known until recently as part of a complex communications network within the cell also plays a direct role in regulating sugar metabolism, according to a new study published on-line in the journal Science Signaling (February 18, 2014). Cell growth and metabolism are tightly controlled processes in our cells. When these functions are disturbed, diseases such as cancer and diabetes occur. Mohamed Soliman, a PhD candidate at the Lunenfeld Tanenbaum Research Institute at...

2012-10-22 07:29:33

SAN DIEGO, Oct. 22, 2012 /PRNewswire/ -- Receptos, Inc., announced today that its selective sphingosine?1? phosphate receptor 1 (S1P1) modulator, RPC1063, has been administered to the first patient in a Phase 2/3 study. RPC01-201, a Phase 2/3 placebo-controlled (Phase 2) and active comparator-controlled (Phase 3) trial, is the first of two planned pivotal studies for RPC1063 in the indication of relapsing multiple sclerosis (RMS). The Phase 2 portion of RPC01-201 is a randomized,...

2012-10-09 07:27:38

SAN DIEGO, Oct. 9, 2012 /PRNewswire/ -- Receptos Inc. today announced that company personnel will deliver two scientific poster presentations about RPC1063 at the Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) annual meeting in Lyon, France, from October 10 to 13, 2012. For a quarter of a century, ECTRIMS has served as Europe's and the world's largest professional organization dedicated to the understanding and treatment of multiple sclerosis...

2012-10-01 02:29:53

SAN DIEGO, Oct. 1, 2012 /PRNewswire/ -- Receptos Inc. today announced that the company is scheduled to present the Featured Presentation at the 10th Annual Discovery on Target Conference at 8:40 a.m. EDT today at the Copley Marriott Hotel in Boston. Mike Hanson, director of structural biology, will speak about the technological advancements in the field that have enabled GPCR structural biology, with an emphasis on the sphingosine 1-phosphate 1 receptor (S1P1) and adenosine a2a receptor...

2012-08-13 06:25:21

SAN DIEGO, Aug. 13, 2012 /PRNewswire/ -- Receptos Inc. today announced that the company is scheduled to present at the 2012 Wedbush PacGrow Life Sciences Management Access Conference at 9:10 a.m. EDT on Wednesday, August 15, 2012, at the Le Parker Meridien Hotel in New York City. Faheem Hasnain, president and chief executive officer, will provide an overview of the company and an update about its Phase 2 clinical development programs for multiple sclerosis and inflammatory bowel disease with...

2012-08-10 02:31:30

Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New treatments specifically attacking cancer cells, but not normal ones, are critical in the fight against cancer. The results, which appear in the July 2012 issue of Experimental Biology and Medicine, demonstrate the role of SK in drug resistance and therapeutic potential of SK...

2012-08-07 23:33:26

Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that afflicts children with many symptoms, including juvenile-onset diabetes. Now a molecule has been identified that's key to the cell stress-modulated inflammation that causes insulin cells to die, report scientists at Washington University School of Medicine in St. Louis, the University of...

2012-05-18 02:24:42

SAN DIEGO, May 18, 2012 /PRNewswire/ -- Receptos Inc. today announced that company personnel will deliver a scientific podium presentation about RPC1063 at the Digestive Disease Week (DDW) annual meeting at 9 a.m. PDT on Sunday, May 20, 2012 at the San Diego Convention Center in San Diego, California. DDW attracts thousands of physicians, researchers, and academics from around the world to share the latest research in gastrointestinal health topics, for which DDW is the premier scientific...

2012-03-01 07:00:00

SAN DIEGO, March 1, 2012 /PRNewswire/ -- Receptos Inc. today announced that the company is scheduled to present at the Cowen and Company 32nd Annual Health Care Conference at noon EST on Wednesday, March 7, 2012, at the Boston Marriott Copley Place in Boston, Massachusetts. Faheem Hasnain, president and chief executive officer, will provide an overview of the company and an update about its clinical development programs. "This is an exciting time at Receptos as we move forward with plans to...

2011-05-11 23:46:03

Research identifies novel metabolic signaling pathway in worms that coordinates the aging response to nutrient availability There is no longer any doubt that dietary restriction (DR) extends lifespan. Many studies have shown that limiting nutrient intake extends lifespan in yeast, worms, flies and as well as postponing age-related diseases in mice. However, scientists are still puzzling over the exact mechanism of DR, convinced its secrets are the key to new therapies for diseases such as...