Latest Liver X receptor Stories
Macular degeneration, the leading cause of blindness in Americans over the age of 50, could be treated using medications traditionally used to lower cholesterol levels.
SAN DIEGO, Aug. 4, 2011 /PRNewswire/ -- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD) announced today the publication of research that uncovered a previously unknown role for a class of molecules that could lead to future advances in immunologic medicine.
UCLA researchers have demonstrated that a key regulator of cholesterol and fat metabolism in the liver also plays an important role in the development of liver fibrosis â€” the build-up of collagen scar tissue that can develop into cirrhosis.
Glucocorticoid drugs are used widely to treat numerous conditions, including rheumatoid arthritis, allergic reactions, asthma, and some forms of cancer, and transplant recipients.
Specific, relatively uncommon variations at a region of human chromosome 8 have recently been linked to fat (lipid) levels in the blood that decrease an individual's risk of atherosclerosis (a disease of the major arterial blood vessels that is a main cause of heart attack and stroke).
Many diseases of brain function, such as epilepsy and schizophrenia, are caused by problems in how neurons communicate with each other.
Tiny insects can shed light on human regulatory processes, U of U-led studies find.
A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach.
Researchers in Austria have developed and tested a synthetic atherosclerosis drug that can reduce the buildup of dangerous blood vessel plaques. First author Adelheid Kratzer of the University of Graz said the encouraging results of this study in mice could lead to a new type of drug to treat or even prevent atherosclerosis without producing the side effect of fatty liver disease, which leads to its own set of problems such as diabetes. The drug, DMHCA, targets proteins called the Liver X...
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