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Latest Long-term potentiation Stories

2014-06-25 10:21:35

Cold Spring Harbor Laboratory There are new clues about malfunctions in brain cells that contribute to intellectual disability and possibly other developmental brain disorders. Professor Linda Van Aelst of Cold Spring Harbor Laboratory (CSHL) has been scrutinizing how the normal version of a protein called OPHN1 helps enable excitatory nerve transmission in the brain, particularly at nerve-cell docking ports containing AMPA receptors (AMPARs). Her team's new work, published June 24 in...

Turning Memory Off And On In Rats To Aid Alzheimer's Research
2014-06-02 14:18:58

Alan McStravick for redorbit.com - Your Universe online Memory is, it could be said, one of the most important keys in the propagation of a species. Without memory, one would be unable to recall fear of a predator or recognize a situation that promises a reward, such as food or an optimal mating situation. There is a flip-side to the coin of memory, too, however. A particularly traumatic experience can too easily be remembered given an environmental catalyst. Losing memory, as is the case...

2014-01-07 23:02:06

Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. Pomona, California (PRWEB) January 07, 2014 Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. The first paper, “A molecular brake controls the magnitude of long-term potentiation,” by Yubin Wang, Guoqi Zhu, Victor...

2013-08-12 14:12:37

A team of neuroscientists has identified a modification to a protein in laboratory mice linked to conditions associated with Alzheimer's Disease. Their findings, which appear in the journal Nature Neuroscience, also point to a potential therapeutic intervention for alleviating memory-related disorders. The research centered on eukaryotic initiation factor 2 alpha (eIF2alpha) and two enzymes that modify it with a phosphate group; this type of modification is termed phosphorylation. The...

2013-03-07 11:22:19

In a new study in Neuron, scientists identified specific key steps in the chain of events that causes stress-related drug relapse. They identified the exact region of the brain where the events take place in rat models and showed that by blocking a step, they could prevent stress-related relapse. All too often, stress turns addiction recovery into relapse, but years of basic brain research have provided scientists with insight that might allow them develop a medicine to help. A new study...

2013-02-13 15:04:21

In the journal PLoS Biology, a team of scientists reports experiments showing how the gene defect of Angelman syndrome disrupts neurological processes that may be needed for memory and learning. In tests in mice, the team showed that a novel compound could restore the healthy processes. In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of...

2012-03-13 22:42:55

A team of scientists has found a novel road-block in the pain pathway, which could be used to treat chronic pain. Their results are published March 13 in the online, open-access journal PLoS Biology. Pain is an important physiological function that protects our bodies from harm. Pain-sensing nerves transduce harmful stimuli into electrical signals and transmit this information to the brain via the spinal cord. However, when these nerves get activated persistently, such as after injury or...

2012-02-09 15:02:46

UC Riverside scientists identify a protein that plays a crucial role in learning and memory Biomedical scientists at the University of California, Riverside have identified a new link between a protein called beta-arrestin and short-term memory that could open new doors for the therapeutic treatment of neurological disorders, particularly Alzheimer's disease. Beta-arrestin is expressed in various cells of the body, including cells of the hippocampus, the region of the brain that is...

2011-12-14 10:18:39

An inhibitory drug reverses seizure damage to neurologic pathways in rats About half of newborns who have seizures go on to have long-term intellectual and memory deficits and cognitive disorders such as autism, but why this occurs has been unknown. In the December 14 Journal of Neuroscience, researchers at Children's Hospital Boston detail how early-life seizures disrupt normal brain development, and show in a rat model that it might be possible to reverse this pathology by giving certain...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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