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Latest Loren Walensky Stories

2012-05-30 08:35:20

Scientists build a synthetic peptide that overcomes cancer cells´ survival defenses Scientists at the Dana-Farber/Children's Hospital Cancer Center have developed an anti-cancer peptide that overcomes the stubborn resistance to chemotherapy and radiation often encountered in certain blood cancers when the disease recurs following initial treatment. The strategy could pave the way for much needed new therapies to treat relapsed and refractory blood cancers, which are difficult to...

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2010-06-21 07:01:27

Prototype drug blocks MCL-1 protein that helps tumors survive treatment Scientists at Dana-Farber Cancer Institute have found a way to disable a common protein that often thwarts chemotherapy treatment of several major forms of cancer. The researchers discovered, surprisingly, that they could exploit a small portion of this anti-death protein, called MCL-1, to make a molecular tool that specifically blocked MCL-1's "pro-survival" action, allowing standard cancer drugs to kill the tumor cells...

2008-10-22 15:00:30

Aileron Therapeutics announced today that one of its proprietary Stapled Peptide compounds, referred to as "BIM-SAHB" in an article published today in Nature, was shown to uniquely target a new and fundamental activation mechanism of the programmed cell death or "apoptotic" pathway. Aileron has advanced an optimized version of the published Stapled Peptide compound into late-stage preclinical studies. In the Nature article, "BAX Activation is Initiated at a Novel Interaction Site,"...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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