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2010-05-27 07:50:00

In a major cancer-research breakthrough, researchers at the McGill University, Department of Biochemistry have discovered that a small segment of a protein that interacts with RNA can control the normal expression of genes "“ including those that are active in cancer. The research, published online on May 26, 2010 by the prestigious journal Nature, has important immediate applications for laboratory research and is another step toward the kind of individualized cancer therapies...

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2010-05-04 09:05:00

Microbes have among smallest genomes, plus unusual interactions with other Archaea In the depths of a former copper mine in Northern California dwell what may be the smallest, most stripped-down forms of life ever discovered. The microbes "“ members of the domain of one-celled creatures called Archaea "“ are smaller than other known microorganisms, rivaled in size only by a microbe that can survive solely as a parasite attached to the outside of other cells. Their genomes,...

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2010-04-08 11:38:37

Researchers at IRB Barcelona refine the process to obtain "photographs" of highly dynamic proteins, an important step in drug design. When designing a drug against a disease, chemists often used detailed plans of the proteins affected and against which the drugs must act. However, about a third of the proteins of our bodies have not yet been "photographed" because they generally vary in form, are in constant movements and have very little structure. This lack of "photographs" hinders the...

2010-03-23 11:35:00

Palo Alto, CA -- To engineer better, more productive crops and develop new drugs to combat disease, scientists look at how the sensor-laden membranes surrounding cells control nutrient and water uptake, secrete toxins, and interact with the environment and neighboring cells to affect growth and development. Remarkably little is known about how proteins interact with these protective structures. With National Science Foundation funding, researchers at the Carnegie Institution's Department of...

2010-03-11 19:54:28

PITTSBURGH -- Repair proteins appear to efficiently scan the genome for errors by jumping like fleas between DNA molecules, sliding along the strands, and perhaps pausing at suspicious spots, say researchers at the University of Pittsburgh, the University of Essex and the University of Vermont who tagged the proteins with quantum dots to watch the action unfold. The findings are available today in Molecular Cell. Everyone is constantly bombarded with environmental toxins that inflict small...

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2010-02-22 16:30:41

An extremely small RNA molecule created by a University of Colorado at Boulder team can catalyze a key reaction needed to synthesize proteins, the building blocks of life. The findings could be a substantial step toward understanding "the very origin of Earthly life," the lead researcher contends. The smallest RNA enzyme ever known to perform a cellular chemical reaction is described in a paper published this week in the Proceedings of the National Academy of Sciences. The paper was written...

2010-02-01 18:05:45

Johns Hopkins scientists believe they may have figured out how genetic snippets called microRNAs are able to shut down the production of some proteins. The issue, they say, is important because the more scientists know about how genes "” the blueprints for proteins "” are regulated, the more likely they are to figure out how to use that information in treating or preventing diseases linked to such regulation, including cancer. In both computer and test-tube studies using fruit-fly...

2010-01-20 14:59:50

In proper society of yesterday, a chaperone ensured that couples maintained appropriate courting rituals. In biology, a group of proteins called chaperonins make sure that proteins are folded properly to carry out their assigned roles in the cells. In a new study in archaea (single-celled organisms without nuclei to enclose their genetic information), a consortium of researchers from Baylor College of Medicine and Stanford University in California discovered how the Group II chaperonins close...

2010-01-20 13:14:32

Scientists at Duke University Medical Center have found some compounds that improve a cell's ability to properly "fold" proteins and could lead to promising drugs for degenerative nerve diseases, including Huntington's disease, Alzheimer's disease and Parkinson's disease. Misfolded proteins in nerve cells (neurons) are a common factor in all of these diseases. The Duke team has identified many new chemicals that activate a master regulator to increase the supply of "protein chaperone"...

2010-01-06 07:59:00

CARLSBAD, Calif., Jan. 6 /PRNewswire/ -- GenVault Corporation, the leader in ambient temperature biosample stabilization, announces the launch of GenTegra(TM) RNA. GenTegra(TM) RNA is an inert chemical matrix that inactivates trace RNase in the liquid phase, providing an added level of RNA stability during sample handling, with or without ice. In the dry-state, GenTegra(TM) preserves RNA integrity by protecting samples from hydrolysis and oxidation, imparts thermal stability at...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.