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Latest LSm Stories

2010-09-01 19:47:31

Bacteria tend to be more frugal when constructing proteins for use outside of the cell versus internally, saving their energy for synthesizing compounds that can be recycled, according to research published in the current issue of the online journal mBioâ“ž¢. "Because extracellular proteins are lost to the environment and not recycled like other cellular proteins, they present a greater burden on the cell, as their amino acids cannot be reutilized during...

2010-08-12 15:49:54

Within a dangerous stomach bacterium, Yale University researchers have discovered an ancient but functioning genetic remnant from a time before DNA existed, they report in the August 13 issue of the journal Science. To the surprise of researchers, this RNA complex seems to play a critical role in the ability of the organism to infect human cells, a job carried out almost exclusively by proteins produced from DNA's instruction manual. "What these cells are doing is using ancient RNA technology...

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2010-06-15 11:04:30

Researchers at University of Ghent, Belgium, and Universitat Autònoma de Barcelona (UAB) develop a new procedure to identify the two extremes of protein molecules and their processing and maturing in in-vivo and ex-vivo massive proteomic studies. The research has been published online at Nature Methods, under the title of "Complementary Positional Proteomics for Screening of Endo- and Exoproteases". The world of proteins is one of the most complex and fundamental in living...

2010-05-27 07:50:00

In a major cancer-research breakthrough, researchers at the McGill University, Department of Biochemistry have discovered that a small segment of a protein that interacts with RNA can control the normal expression of genes "“ including those that are active in cancer. The research, published online on May 26, 2010 by the prestigious journal Nature, has important immediate applications for laboratory research and is another step toward the kind of individualized cancer therapies...

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2010-05-04 09:05:00

Microbes have among smallest genomes, plus unusual interactions with other Archaea In the depths of a former copper mine in Northern California dwell what may be the smallest, most stripped-down forms of life ever discovered. The microbes "“ members of the domain of one-celled creatures called Archaea "“ are smaller than other known microorganisms, rivaled in size only by a microbe that can survive solely as a parasite attached to the outside of other cells. Their genomes,...

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2010-04-08 11:38:37

Researchers at IRB Barcelona refine the process to obtain "photographs" of highly dynamic proteins, an important step in drug design. When designing a drug against a disease, chemists often used detailed plans of the proteins affected and against which the drugs must act. However, about a third of the proteins of our bodies have not yet been "photographed" because they generally vary in form, are in constant movements and have very little structure. This lack of "photographs" hinders the...

2010-03-23 11:35:00

Palo Alto, CA -- To engineer better, more productive crops and develop new drugs to combat disease, scientists look at how the sensor-laden membranes surrounding cells control nutrient and water uptake, secrete toxins, and interact with the environment and neighboring cells to affect growth and development. Remarkably little is known about how proteins interact with these protective structures. With National Science Foundation funding, researchers at the Carnegie Institution's Department of...

2010-03-11 19:54:28

PITTSBURGH -- Repair proteins appear to efficiently scan the genome for errors by jumping like fleas between DNA molecules, sliding along the strands, and perhaps pausing at suspicious spots, say researchers at the University of Pittsburgh, the University of Essex and the University of Vermont who tagged the proteins with quantum dots to watch the action unfold. The findings are available today in Molecular Cell. Everyone is constantly bombarded with environmental toxins that inflict small...

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2010-02-22 16:30:41

An extremely small RNA molecule created by a University of Colorado at Boulder team can catalyze a key reaction needed to synthesize proteins, the building blocks of life. The findings could be a substantial step toward understanding "the very origin of Earthly life," the lead researcher contends. The smallest RNA enzyme ever known to perform a cellular chemical reaction is described in a paper published this week in the Proceedings of the National Academy of Sciences. The paper was written...

2010-02-01 18:05:45

Johns Hopkins scientists believe they may have figured out how genetic snippets called microRNAs are able to shut down the production of some proteins. The issue, they say, is important because the more scientists know about how genes "” the blueprints for proteins "” are regulated, the more likely they are to figure out how to use that information in treating or preventing diseases linked to such regulation, including cancer. In both computer and test-tube studies using fruit-fly...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.