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2013-09-30 10:19:30

A research team centered at Brown University has compiled the largest and most stringently validated list of RNA editing sites in the fruit fly Drosophila melanogaster, a stalwart of biological research. Their research, which yielded several insights into the model organism's fundamental biology, appears Sept. 29 in Nature Structural & Molecular Biology. The "master list" totals 3,581 sites in which the enzyme ADAR might swap an "A" nucleotide for a "G" in an RNA molecule. Such a...

Unraveling Secrets Of The Mechanism That Snips Our Genes
2013-09-27 09:50:05

Brandeis University Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing. These conditions are difficult to prevent because scientists are still grasping to understand how the splicing process works. Now, researchers from Brandeis University and the University of Massachusetts Medical School have teamed up to unravel...

RNA Stores More Functional Genome Data Than Previously Thought
2013-07-12 04:51:08

redOrbit Staff & Wire Reports - Your Universe Online Contrary to the belief that a large percentage of the human genome contains "junk" material, a team of Australian scientists report they have discovered an unexpectedly high proportion of functional elements that have been conserved through evolution. According to Dr. Martin Smith and Professor John Mattick of the Garvan Institute of Medical Research in Sydney, less than 1.5 percent of the human genome is devoted to conventional...

2013-06-06 20:02:51

Structural and molecular differences between human Argonaute proteins reveal essential elements for RNA-slicing Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression. Human Argonaute-2 (hAgo2) is known as "slicer" for its unique ability among the 4 human Argonaute proteins to directly cut messenger RNA -- which carries the information coded in genomic DNA to make a...

2013-04-08 12:13:20

3-year study offers new evidence about where scientists should be looking A structural biologist at the Florida State University College of Medicine has made discoveries that could lead scientists a step closer to understanding how life first emerged on Earth billions of years ago. Professor Michael Blaber and his team produced data supporting the idea that 10 amino acids believed to exist on Earth around 4 billion years ago were capable of forming foldable proteins in a high-salt...

2013-03-04 23:05:52

St. Jude Children's Research Hospital ties mutations in 2 genes to the death of motor neurons associated with ALS, or Lou Gehrig's disease, and other devastating neurodegenerative problems A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases. The same mutation occurred in both genes and led to the...

Mysterious Microbial Community Unveiled Using Infrared Spectromicroscopy
2013-01-22 09:45:35

DOE/Lawrence Berkeley National Laboratory Berkeley Lab scientists join an international collaboration to understand how archaea and bacteria work together deep in a cold sulfur spring In the fall of 2010, Hoi-Ying Holman of the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) was approached by an international team researching a mysterious microbial community discovered deep in cold sulfur springs in southern Germany. "They told me what they were doing...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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