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Last updated on April 18, 2014 at 6:03 EDT

Latest LSm Stories

RNA Stores More Functional Genome Data Than Previously Thought
2013-07-12 04:51:08

redOrbit Staff & Wire Reports - Your Universe Online Contrary to the belief that a large percentage of the human genome contains "junk" material, a team of Australian scientists report they have discovered an unexpectedly high proportion of functional elements that have been conserved through evolution. According to Dr. Martin Smith and Professor John Mattick of the Garvan Institute of Medical Research in Sydney, less than 1.5 percent of the human genome is devoted to conventional...

2013-06-06 20:02:51

Structural and molecular differences between human Argonaute proteins reveal essential elements for RNA-slicing Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression. Human Argonaute-2 (hAgo2) is known as "slicer" for its unique ability among the 4 human Argonaute proteins to directly cut messenger RNA -- which carries the information coded in genomic DNA to make a...

2013-04-08 12:13:20

3-year study offers new evidence about where scientists should be looking A structural biologist at the Florida State University College of Medicine has made discoveries that could lead scientists a step closer to understanding how life first emerged on Earth billions of years ago. Professor Michael Blaber and his team produced data supporting the idea that 10 amino acids believed to exist on Earth around 4 billion years ago were capable of forming foldable proteins in a high-salt...

2013-03-20 20:22:52

Isis to host an investor event and live webcast at 7:30 am PT on Thursday, March 21 in San Diego CARLSBAD, Calif., March 20, 2013 /PRNewswire/ -- Isis Pharmaceuticals, Inc. (NASDAQ: ISIS) announced that data from the Phase 1 study of ISIS-SMN(Rx) in children with spinal muscular atrophy (SMA) were presented today at the 65(th) American Academy of Neurology (AAN) Annual Meeting by Dr. Claudia Chiriboga, from Columbia University Medical Center. In the presentation, Dr. Chiriboga...

2013-03-04 23:05:52

St. Jude Children's Research Hospital ties mutations in 2 genes to the death of motor neurons associated with ALS, or Lou Gehrig's disease, and other devastating neurodegenerative problems A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases. The same mutation occurred in both genes and led to the...

2013-03-03 12:20:33

St. Jude Children's Research Hospital ties mutations in two genes to the death of motor neurons associated with ALS, or Lou Gehrig's disease, and other devastating neurodegenerative problems MEMPHIS, Tenn., March 3, 2013 /PRNewswire-USNewswire/ -- A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases. The...

2013-01-31 12:28:39

CAMBRIDGE, England, Jan. 31, 2013 /PRNewswire/ -- One of the most innovative biotechnologies of the last decade has recently been developed. SINEUP allows scientists, for the first time, to target individual genes in cells to knockup, or increase, the amount of protein they make. The technique will improve Protein manufacture, analyse the function of genes and engineer improved cell function. This novel technology is based on pioneering research in the lab of Dr Stefano Gustincich...

Mysterious Microbial Community Unveiled Using Infrared Spectromicroscopy
2013-01-22 09:45:35

DOE/Lawrence Berkeley National Laboratory Berkeley Lab scientists join an international collaboration to understand how archaea and bacteria work together deep in a cold sulfur spring In the fall of 2010, Hoi-Ying Holman of the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) was approached by an international team researching a mysterious microbial community discovered deep in cold sulfur springs in southern Germany. "They told me what they were doing...

2012-10-24 15:21:26

SAVAGE, Md., Oct. 24, 2012 /PRNewswire/ -- Chesapeake PERL has been awarded a contract to develop the human nerve agent bioscavenger butyrylcholinesterase (BChE) as a potential nerve agent countermeasure for the Defense Threat Reduction Agency (DTRA). The contract will fund development of a recombinant human BChE and its production in C-PERL's PERLXpress high efficiency protein manufacturing system. C-PERL will collaborate with the US Army Medical Research Institute of Chemical Defense...

2012-10-11 12:57:01

Experimental studies of ancestral visual pigments and their mutational variants cast doubt on simplifying assumptions widely used in evolutionary studies of proteins A key assumption that biologists have relied on widely over the past quarter-century in studying the evolution of protein molecules is "highly questionable," according to an article published in the November issue of BioScience. The article, by Shozo Yokoyama, a vision researcher at Emory University, summarizes experimental...