Quantcast

Latest LSm Stories

2012-05-18 23:58:51

Discovery alters prevailing view of splicing regulation and has implications for splicing mutations associated with disease There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting exception uncovered by the study concerns the way in which a newly produced RNA molecule is cut and pasted at precise locations called splice...

2012-05-18 02:18:32

Genetic discovery will revolutionize understanding of gene expression Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases. Now, researchers at Weill Cornell Medical College have made a discovery that once again forces us to rewrite our textbooks. This time, however, the findings...

2012-04-27 22:18:04

Novel regulatory molecules called mirror-microRNAs control multiple aspects of brain function Our genes control many aspects of who we are – from the colour of our hair to our vulnerability to certain diseases – but how are the genes, and consequently the proteins they make themselves controlled? Researchers have discovered a new group of molecules which control some of the fundamental processes behind memory function and may hold the key to developing new therapies for...

2012-04-25 12:03:57

Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design a step further; using computational methods, they have created the first custom-designed protein crystal. Picking an ambitious design target with challenging features, the researchers´ success bodes well for the technique´s use in better understanding proteins´ makeup...

2012-04-24 22:54:30

Research also finds how RNA editing enzyme activity varies with temperature Because a function of RNA is to be translated as the genetic instructions for the protein-making machinery of cells, RNA editing is the body's way of fine-tuning the proteins it produces, allowing us to adapt. The enzyme ADAR, which does this editing job in the nervous system of creatures ranging from mice to men, even edits itself. In a new study that examined the self-editing process and locked it down at two...

2012-03-26 11:03:13

Few molecules are more interesting than DNA–except of course RNA. After two decades of research, that "other macromolecule" is no longer considered a mere messenger between glamorous DNA and protein-synthesizing machines. We now know that RNA has been leading a secret life, regulating gene expression and partnering with proteins to form catalytic ribonucleoprotein (RNP) complexes. One of those RNPs is telomerase, an enzyme that maintains chromosome integrity. In the March 25, 2012,...

2012-03-09 01:43:43

Max Planck scientists identify key player of protein folding Proteins are the molecular building blocks and machinery of cells and involved in practically all biological processes. To fulfil their tasks, they need to be folded into a complicated three-dimensional structure. Scientists from the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, have now analysed one of the key players of this folding process: the molecular chaperone DnaK. “The...

2012-03-05 13:11:22

Discovery paves the way for new synthesis of antibiotics Researchers working at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have used powerful X-rays to help decipher how certain natural antibiotics defy a longstanding set of chemical rules — a mechanism that has baffled organic chemists for decades. Their result, reported today in Nature, details how five carbon atoms and one oxygen atom in the structure of lasalocid, a natural antibiotic produced...

2012-03-02 13:00:00

Media integration and events community kicks off voting for awards contest representing the top influencers in the SMB channel. Redmond, WA (PRWEB) March 02, 2012 SMB Nation announced today at its MVP Nation event, that it has officially opened voting for its SMB 150, representing the top 150 influencers in the SMB channel. In addition, for the first time, the media integration and events community, in conjunction with SMB Technology Network (SMBTN), will be holding a live Gala Event on May...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
Related