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Latest LSm Stories

2012-01-09 11:31:12

Scientists find that small, high-probability mutations can produce complex system Much of what living cells do is carried out by "molecular machines" — physical complexes of specialized proteins working together to carry out some biological function. How the minute steps of evolution produced these constructions has long puzzled scientists, and provided a favorite target for creationists. In a study published early online on Sunday, January 8, in Nature, a team of scientists from...

2011-12-20 22:14:38

Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process. Purdue University biologists led a team that revealed how a pair of proteins from the bacteria Legionella pneumophila, which causes Legionnaires disease, alters a host protein in order to divert raw materials within the cell for use in building and disguising a large structure that houses the bacteria as it replicates. Zhao-Qing Luo, the...

2011-12-12 13:28:32

Discovery of subcellular processing location and target signal of cyclotide kalata B1 Many plants produce compounds that serve as a defense against predators or pathogens. Some are also used by humans for a variety of beneficial purposes, such as in medicines. As recently as the early 1990s, a unique class of proteins previously unknown to science, the cyclotides, was discovered. First noted through African tribal use as a tea given to speed up delivery during childbirth, cyclotides have...

2011-11-15 19:23:37

Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a universally fatal neurodegenerative disease. Mutations in two related proteins, TDP-43 and FUS, cause some forms of ALS. Specifically, these two proteins are RNA-binding proteins that connect to RNA to regulate the translation of proteins and other cellular functions such as RNA splicing and editing. In a new study, researchers at the Perelman School of Medicine at the University of Pennsylvania discovered additional human...

2011-10-05 19:32:27

Findings reveal that deficiency of the SMN protein in peripheral tissues might also contribute to SMA pathology A new study from Cold Spring Harbor Laboratory (CSHL) reports surprising results that suggest that the devastating neuromuscular disease, spinal muscular atrophy (SMA), might not exclusively affect the motor neurons in the spinal cord as has long been thought. The new findings suggest that defects in peripheral tissues such as liver, muscle, heart, etc., might also contribute to...

2011-08-16 23:08:53

As part of a joint research effort with the University of Michigan, scientists from the Florida campus of The Scripps Research Institute have for the first time defined the structure of one of the cell's most basic engines, which is required for cell growth, as it assembles from its components. The study reveals a series of redundant mechanisms that assure production of these critical structures while avoiding any missteps that could lead to their destruction or to the production of incorrect...

2011-08-15 12:18:10

Salmonella cells have hijacked the protein-building process to maintain their ability to cause illness, new research suggests. Scientists say that these bacteria have modified what has long been considered typical cell behavior by using a beta form of an amino acid "“ as opposed to an alpha form "“ during the act of making proteins. Beta versions of amino acids occur in nature under rare and specific circumstances, but have never been observed as part of protein synthesis. Before...

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2011-08-05 09:26:04

Scientists at the University of York, using an 'amino acid time capsule', have led the largest ever program to date the British Quaternary period, stretching back nearly three million years. It is the first widespread application of refinements of the 40-year-old technique of amino acid geochronology. The refined method, developed at York's BioArCh laboratories, measures the breakdown of a closed system of protein in fossil snail shells, and provides a method of dating archaeological and...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.