Latest Luciferase Stories
A unique new probe based on luciferase, the enzyme that gives fireflies their glow, enables researchers to monitor hydrogen peroxide levels in mice and thereby track the progression of infectious diseases or cancerous tumors without harming the animals or even having to shave their fur.
The enzyme that makes fireflies glow is lighting up the scientific path toward a long-sought new medical imaging agent to better monitor treatment with heparin, the blood thinner that millions of people take to prevent or treat blood clots.
The new Renilla-Gloâ„¢ Luciferase Assay brings the convenience of the â€œadd, mix, measureâ€ assay format to applications using the sea pansy (Renilla reniformis) luciferase.
If you regularly experience the pangs of jet lag or a crazy work schedule, then you may not be the biggest fan of your body's biological clock.
In a proof of principal study in mice, scientists at Johns Hopkins and the Virginia Commonwealth University (VCU) have shown that a set of genetic instructions encased in a nanoparticle can be used as an "ignition switch" to rev up gene activity that aids cancer detection and treatment.
Mindin has an indispensable role in both innate and adaptive immunity.
GAITHERSBURG, Md., March 16 /PRNewswire/ -- Scientists who want to ensure reliable chemiluminescent sensitivity and specificity measurements for their tests should consider the MicroLumi-L2 glow microplate luminometer, the successor to the popular MicroLumi-XS luminometer, and the LRM168-96 Luminometer Reference Microplate, both designed and manufactured in the USA by Harta Instruments, Gaithersburg, MD.
A study by National Institutes of Health (NIH) researchers has revealed surprising new insights into the process used to initially identify an experimental drug now being tested in people with cystic fibrosis and muscular dystrophy.
By Fleshker, Shimrit Preise, Dina; Kalchenko, Vyacheslav; Scherz, Avigdor; Salomon, Yoram ABSTRACT This study hypothesized that success rate assessment of vascular targeted photodynamic therapy (VTP) of solid tumors 24 h posttreatment may allow prompt administration of a second treatment in case of failure, increasing the overall success rate.
By Yeom, Chan Joo Chung, June-Key; Kang, Joo Hyun; Jeon, Yong Hyun; Kim, Kwang Il; Jin, Yong Nan; Lee, You Mie; Jeong, Jae Min; Lee, Dong Soo Hypoxia-inducible factor-1 (HIF-1) is a transcription factor of hypoxic response in cancer cells and is associated with tumor progression, angiogenesis, metastasis, and resistance to therapy.
Fireflies, also known as lightning bugs, are nocturnal, luminous beetles of the family Lampyridae. These names come from the fact that some species as adults emit flashes of light to attract mates, using special light-emitting organs in the abdomen. The enzyme luciferase acts on luciferin to stimulate light emission. This reaction is of scientific interest, and genes coding for these substances have been spliced into many different organisms. Many species, especially in the genus Photinus,...
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