Latest Lymph node Stories

Study refutes controversy about technique in delicate head, neck regionA common technique for determining whether melanoma has spread can be used safely and effectively even in tumors from the head and neck area, according to a new study from the University of Michigan Comprehensive Cancer Center.Sentinel lymph node biopsy involves injecting a special dye to identify the first node where cancer would likely spread. If that node is clean, patients can avoid further debilitating surgery to...

Study reported in Journal of the American Medical AssociationA new study shows that removing lymph nodes due to the presence of occult, or microscopic, cancer cells found in the sentinel lymph node "“ the one closest to the tumor -- has no impact on survival outcomes of women with early-stage breast cancer. The principal investigator of the study is Armando E. Giuliano, MD, of Cedars-Sinai, who already is renowned for his clinical expertise and for his seminal research on lymph node removal...

There are many kinds of cancers of the immune system, but one, Activated B-Cell Diffuse Large B-Cell Lymphoma, or ABC-DLBCL, is particularly common and pernicious. Researchers at the University of Pennsylvania's School of Veterinary Medicine have shown for the first time that dogs that develop this disease spontaneously share the same aberrant activation of a critical intracellular pathway with humans. They also found that a drug designed to disrupt this pathway helps to kill tumor cells in...

Cancer cells do not grow equally well everywhere in the body. Often, they first create the conditions in which they can grow. Many years ago researchers discovered that solid tumors attract blood vessels to ensure their supply of nutrients by secreting specific factors. Now the immunologist Dr. Uta Höpken (Tumor and Immunogenetics Research Group at the Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch in the Helmholtz Association) and the hematologist Dr. Armin Rehm...

Scientists close in on molecular moves that let tumor cells act as stowaways in lymphatic systemCancer has a mighty big bag of tricks that it uses to evade the body's natural defense mechanisms and proliferate. Among those tricks is one that allows tumor cells to turn the intricate and extensive system of lymphatic vessels into something of a highway to metastasis. Yet research unveiled this week may aid in the development of therapeutics that will put the brakes on such cancer spread, and...

ST. LOUIS, April 8, 2011 /PRNewswire-USNewswire/ -- Saint Louis University researchers have identified a novel mechanism to control the traffic of cells and fluid from tissues to lymphatic vessels. It may be possible to harness this mechanism to fight cancer spread from one organ to another organ and improve the effectiveness of vaccines. The lymphatic system is an extensive fluid transit system, consisting of vessels in the body. It defends the body against infection. Cancer cells and...

(Ivanhoe Newswire)  A new laser technique could help prevent cancer from spreading in humans.In the study, Dr. Tuomas Tammela and his colleagues at the University of Helsinki, Finland, wanted to find out if they could help stop a cancer from spreading by using a laser therapy to destroy cancer cells lodged in lymphatic vessels.The scientists experimented with PDT Photodynamic therapy (PDT). During PDT doctors inject a light-activated drug into the tumors and then turn an infrared laser on...

Photodynamic ablation of lymphatic vessels and intralymphatic cancer cells prevents metastasisTumor cells have several routes that enable them to move from the primary tumor to distant tissues, a process called metastasis. It is metastasis of the primary tumor that kills most cancer patients. One of the least studied routes of metastasis is the lymphatic system. Many tumors produce factors that promote the formation of new lymphatic vessels (lymphangiogenesis). The newly formed lymphatic...

Among patients with early-stage breast cancer that had spread to a nearby lymph node and who received treatment that included lumpectomy and radiation therapy, women who just had the sentinel lymph node removed (the first lymph node to which cancer is likely to spread from the primary tumor) did not have worse survival than women who had more extensive axillary lymph node dissection (surgery to remove lymph nodes found in the armpit), according to a study in the February 9 issue of...

Process yields higher throughput; quicker, more-consistent diagnosesResearchers are leveraging Ohio Supercomputer Center resources to develop computer-assisted diagnosis tools that will provide pathologists grading Follicular Lymphoma samples with quicker, more consistently accurate diagnoses."The advent of digital whole-slide scanners in recent years has spurred a revolution in imaging technology for histopathology," according to Metin N. Gurcan, Ph.D., an associate professor of Biomedical...