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Latest Lymphocyte Stories

2013-01-03 15:28:29

Researchers from the RIKEN Research Centre for Allergy and Immunology in Japan report today that they have succeeded for the first time in creating cancer-specific, immune system cells called killer T lymphocytes, from induced pluripotent stem cells (iPS cells). To create these killer cells, the team first had to reprogram T lymphocytes specialized in killing a certain type of cancer, into iPS cells. The iPS cells then generated fully active, cancer-specific T lymphocytes. These lymphocytes...

2012-12-19 11:30:11

Scientists from the AIDS Research Institute IrsiCaixa have identified how HIV, the virus that causes AIDS, enters the cells of the immune system enabling it to be dispersed throughout an organism. The new study is published December 18 in the open access journal PLOS Biology. One of the reasons why we do not yet have a cure for HIV infection is that the virus infects cells of the immune system that would normally fight such an infection. The main targets of HIV are white blood cells named...

2012-10-22 10:40:31

Certain immune cell receptors are more common than mere chance would dictate. New research shows why Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats is to randomly combine DNA segments for the production of receptors on lymphocytes — a type of white blood cell. The number of possible receptors that can be...

2012-09-10 23:01:05

Xtalks presents a live webinar on September 20, 2012 at 11:00am EDT on Immune Profiling Tools for Drug Discovery and Clinical Monitoring, featuring Yoav Peretz Ph.D., Principal Scientist, Caprion/IMMUNECARTA Services, as our keynote speaker. Register for the webinar at http://xtks.in/xto-512. Toronto, Canada (PRWEB) September 10, 2012 PD-1 is a key immunological checkpoint expressed by activated T cells. PD-1 mediates immunosuppression by modulating the TCR signaling machinery, thus...

Lack Of Single Protein Results In Persistent Viral Infection
2012-06-13 21:16:44

Scientists from The Scripps Research Institute have shown a single protein can make the difference between an infection clearing out of the body or persisting for life. The results also show where the defects occur in the immune system without the protein and offer the possibility that targeting this signaling pathway could be beneficial for treatment of persistent viral infections in humans. Currently hundreds of millions of people around the world are afflicted with persistent viral...

2012-05-03 19:04:58

A new study helps to resolve an ongoing controversy about whether Langerhans cells (LCs) in human skin function to suppress the immune response and promote tolerance to normal human skin and its "friendly" microbial flora or mobilize a lethal attack against harmful foreign invaders. The research, published online May 3rd in the journal Immunity by Cell Press, reveals that, depending on the situation, these versatile immune cells can perform either function. Adult human skin contains...

2012-04-30 20:08:11

Finding of an amplification defense mechanism may help research on brain infections, tumors & autoimmune attacks — and settle a debate in immunology Like a police officer calling for backup while also keeping a strong hold on a suspected criminal, immune cells in the brain take a two-tier approach to fighting off a threat, new research from the University of Michigan Health System finds. For the first time, the scientists managed to capture that reaction in action, showing how...

2012-04-13 11:31:12

Expanding on previous research providing proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers have now demonstrated that these cells can actually attack HIV-infected cells in a living organism. The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal...

2012-03-21 14:32:43

Powerful immunosupressant cells obtained from cheek tissue Powerful new cells created by Cardiff University scientists from cheek lining tissue could offer the answer to disorders of the immune system. While the body's immune system protects against many diseases, it can also be harmful. Using white blood cells (lymphocytes), the system can attack insulin-producing cells, causing diabetes, or cause the body to reject transplanted organs. A team from Cardiff's School of Dentistry led...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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