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Latest Lymphocyte Stories

2012-09-10 23:01:05

Xtalks presents a live webinar on September 20, 2012 at 11:00am EDT on Immune Profiling Tools for Drug Discovery and Clinical Monitoring, featuring Yoav Peretz Ph.D., Principal Scientist, Caprion/IMMUNECARTA Services, as our keynote speaker. Register for the webinar at http://xtks.in/xto-512. Toronto, Canada (PRWEB) September 10, 2012 PD-1 is a key immunological checkpoint expressed by activated T cells. PD-1 mediates immunosuppression by modulating the TCR signaling machinery, thus...

Lack Of Single Protein Results In Persistent Viral Infection
2012-06-13 21:16:44

Scientists from The Scripps Research Institute have shown a single protein can make the difference between an infection clearing out of the body or persisting for life. The results also show where the defects occur in the immune system without the protein and offer the possibility that targeting this signaling pathway could be beneficial for treatment of persistent viral infections in humans. Currently hundreds of millions of people around the world are afflicted with persistent viral...

2012-05-03 19:04:58

A new study helps to resolve an ongoing controversy about whether Langerhans cells (LCs) in human skin function to suppress the immune response and promote tolerance to normal human skin and its "friendly" microbial flora or mobilize a lethal attack against harmful foreign invaders. The research, published online May 3rd in the journal Immunity by Cell Press, reveals that, depending on the situation, these versatile immune cells can perform either function. Adult human skin contains...

2012-04-30 20:08:11

Finding of an amplification defense mechanism may help research on brain infections, tumors & autoimmune attacks — and settle a debate in immunology Like a police officer calling for backup while also keeping a strong hold on a suspected criminal, immune cells in the brain take a two-tier approach to fighting off a threat, new research from the University of Michigan Health System finds. For the first time, the scientists managed to capture that reaction in action, showing how...

2012-04-13 11:31:12

Expanding on previous research providing proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers have now demonstrated that these cells can actually attack HIV-infected cells in a living organism. The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal...

2012-03-21 14:32:43

Powerful immunosupressant cells obtained from cheek tissue Powerful new cells created by Cardiff University scientists from cheek lining tissue could offer the answer to disorders of the immune system. While the body's immune system protects against many diseases, it can also be harmful. Using white blood cells (lymphocytes), the system can attack insulin-producing cells, causing diabetes, or cause the body to reject transplanted organs. A team from Cardiff's School of Dentistry led...

2012-03-06 14:05:03

A new study provides evidence that a critical type of immune cell can develop in human tonsils. The cells, called T lymphocytes, or T cells, have been thought to develop only in the thymus, an organ of the immune system that sits on the heart. The study, led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), could improve the understanding of T-cell cancers and...

2012-02-27 07:24:19

Study in Nature Medicine could lead to novel therapy for cancer In a study published in Nature Medicine, Loyola researchers report on a promising new technique that potentially could turn immune system killer T cells into more effective weapons against infections and possibly cancer. The technique involves delivering DNA into the immune system's instructor cells. The DNA directs these cells to overproduce a specific protein that jumpstarts important killer T cells. These killer cells...

2012-02-10 00:02:57

A scientific team led by researchers at the University of Geneva (UNIGE) and the Charité Berlin Medical University has made a completely unprecedented discovery showing how much our immune system is provoked into action when confronted by viral intruders. The possibility of exploiting this mechanism in vaccines holds promise for the development of new ways of preventing and treating infectious diseases and cancer. Killer T cells — also called cytotoxic T lymphocytes...

2012-02-08 14:50:52

Immunological diseases, such as eczema and asthma, are on the increase in westernised society and represent a major challenge for 21st century medicine. A new study has shown, for the first time, that growing up on a farm directly affects the regulation of the immune system and causes a reduction in the immunological responses to food proteins. The research, led by the University of Bristol's School of Veterinary Sciences, found that spending early life in a complex farm environment...