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Last updated on April 17, 2014 at 1:21 EDT

Latest Lymphocyte Stories

2012-02-07 06:57:06

(Ivanhoe Newswire) -- T lymphocytes (T Cells) are supposed to be screened for their ability to recognize normal tissue during development. These auto-reactive cells are normally removed, but some slip by safeguards and could contribute to autoimmune disease. According to Kai Wucherpfennig at the Dana-Farber Cancer Institute and Harvard Medical School, auto-reactive T cells from patients with type 1 diabetes and multiple sclerosis bound their targets more weakly than helpful T cells that...

2012-02-06 22:37:07

Susceptibility to anthrax toxin is a heritable genetic trait that may vary tremendously among individuals, according to a new study by researchers at the Stanford University School of Medicine. Among 234 people studied, the cells of three people were virtually insensitive to the toxin, while the cells of some people were hundreds of times more sensitive than those of others. The findings may have important implications for national security, as people known to be more resistant to anthrax...

2012-01-25 12:45:20

Leukemic cutaneous T-cell lymphoma (L-CTCL) is a leukemia arising from T-cells, a type of white blood cell. This cancer can involve the skin and other organs, and patients often die within three years. Rachael A. Clark, MD, PhD, BWH assistant professor of dermatology and associate dermatologist and Thomas Kupper, MD, BWH Department of Dermatology chairman and their colleagues now report a new study that low-dose Campath (alemtuzumab) not only treats patients with L-CTCL but does so without...

2012-01-21 00:13:05

These new data are an essential step towards understanding the operation of these key cells in the immune system, and they could provide a new therapeutic approach to fighting infection. They also suggest that the operation of NK cells must be precisely regulated to guarantee an optimum immune reaction. Details of this work are published in the 20 January 2012 issue of the journal Science. Our bodies are subject to attack by many different infectious particles (bacteria, viruses, etc.),...

2012-01-03 10:08:00

SEATTLE, Jan. 3, 2012 /PRNewswire/ -- Adaptive TCR Corporation, a leading provider of next generation sequencing assays for the adaptive immune system marketed under the brand name immunoSEQ, announced today it has changed its name to Adaptive Biotechnologies Corporation effective immediately. (Logo: http://photos.prnewswire.com/prnh/20120103/SF28632LOGO) The name change reflects the expanded capabilities of the company's original immune profiling business as well as the...

2011-12-23 10:17:41

A research team led by Glenn Rall at the Fox Chase Cancer Center in Philadelphia, PA developed a novel mouse model to show that a fatal central nervous system (CNS) disease can be caused by a pathogen that does not replicate in the CNS. The results of this new study are published December 22nd in the Open Access journal PLoS Pathogens. The authors found that the immune response induced in response to a peripheral viral infection can be "mis-recruited" to the brain, where these activated...

2011-12-15 17:19:14

Steve Reiner, MD, professor of Medicine, and Burton Barnett, a doctoral student in the Reiner lab at the Perelman School of Medicine at the University of Pennsylvania, have shown how immune cells, called B lymphocytes, are able to produce daughter cells that are not equal, a finding that might explain how lifelong antibodies are made after vaccination. How do immune cells make daughter cells that are different form one another, rather than splitting into identical daughter cells? The...

2011-12-14 02:28:19

Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion. Yet exhausted immune cells can be revived after the introduction of fresh cells that act like coaches giving a pep talk, researchers at Emory Vaccine Center have found. Their findings provide support for an emerging strategy for treating chronic infections: infusing immune cells back into patients after a period of...

2011-12-12 13:20:35

Treatment with patients' own cells may prevent infections commonly seen following treatment and prolong remission A new treatment using leukemia patients' own infection-fighting cells appears to protect them from infections and cancer recurrence following treatment with fludarabine-based chemotherapy, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The new process is a step toward eliminating the harsh side effects that result from the...

2011-12-10 18:00:00

CLEVELAND, Dec. 10, 2011 /PRNewswire/ -- Researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine presented new research findings in 25 presentations this weekend at the 53rd Annual Meeting of the American Society of Hematology (ASH) at the San Diego Convention Center. "The breadth and depth of this innovative cancer research presented at ASH is truly outstanding," says Stan Gerson, MD, Director...