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Latest Lysophosphatidic acid Stories

2014-03-05 08:28:45

Publication Further Validates Lpath's Approach to Targeting Bioactive Lipids for Drug Discovery SAN DIEGO, March 5, 2014 /PRNewswire/ -- Lpath, Inc. (NASDAQ: LPTN), the industry leader in bioactive lipid-targeted therapeutics, has brought scientists one step closer to finding a potential treatment for traumatic brain injury (TBI) with a recent publication showing that Lpathomab(TM), a therapeutic antibody, reverses much of the damage caused by trauma to the nervous system. As...

2011-09-07 19:55:41

An excess of a natural molecule can bring about the devastating ℠water on the brain´ condition in mice and blocking its action can prevent the effect Scientists at The Scripps Research Institute have found what may be a major cause of congenital hydrocephalus, one of the most common neurological disorders of childhood that produces mental debilitation and sometimes death in premature and newborn children. The research appears in the September 7, 2011, issue of the journal...

2011-01-05 10:00:00

SAN DIEGO, Jan. 5, 2011 /PRNewswire/ -- Amira Pharmaceuticals, Inc. announced today the publication of its findings in the Journal of Pharmacology and Experimental Therapeutics (JPET) which describes the biologic effects and the characterization of AM095, a lysophosphatidic acid (LPA) receptor 1 antagonist, in various in vitro and in vivo models of fibrotic disease. "Activation of the LPA1 receptor by LPA has been implicated in a number of disease processes, including tissue fibrosis,"...

2010-12-15 10:00:00

SAN DIEGO, Dec. 15, 2010 /PRNewswire/ -- Amira Pharmaceuticals, Inc. announced today that it has successfully identified a novel pre-clinical candidate for its newest lysophosphatidic acid (LPA)-related program, autotaxin. Autotaxin is an enzyme upstream from LPA receptors and has been implicated in a number of diseases including rheumatoid arthritis, glioblastoma, lung, breast, ovarian and thyroid cancers. "We are pleased to announce that we have identified an orally bioavailable and...

2009-06-10 13:45:00

New mouse models will help deploy experimental drugs against LPA receptors, autotaxinFour suspects often found at the scene of the crime in cancer are guilty of the initiation and progression of breast cancer in mice that are resistant to the disease, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the June edition of Cancer Cell."We have a smoking gun" that shows it's no coincidence the three protein receptors and the enzyme that makes them are...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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