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Latest M cell Stories

2012-06-18 11:28:54

Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses. M cells act like "conveyor belts," ingesting bacteria and transporting substances from the gut into Peyer's patches, specialized tissues resembling lymph nodes in the intestines. Better knowledge of M cells' properties could aid research on oral vaccines and inflammatory bowel diseases. A team of researchers at Emory...

2012-04-23 13:27:59

Researchers at the Hebrew University of Jerusalem and other institutions have identified two distinguishable groups of genes: those that produce very abundant biochemical products in the cell and function properly in the majority of biological processes, and a flexible subset that might have abnormal function in a disease. They demonstrated that these two groups can be found among various organisms and cell types, including stem cells and cancer cells. One set of genes is a robust...

2012-03-14 13:55:20

With every meal, immune cells in the intestine stand like sentries at a citadel, turning away harmful bacteria but allowing vitamins and nutrients to pass. Now, researchers at Washington University School of Medicine in St. Louis have identified the cells that chaperone food antigens, or proteins, in the intestine so that the immune system doesn't mount an attack. Their discovery, in mice, sheds new light on the function of goblet cells that line the intestine, and provides scientists...

2011-03-17 20:18:18

Scientists at IRB Barcelona report new data in support of link between stem cells and cancer, opening door to new tools for diagnosis and treatment Colorectal cancer cells trigger a set of genes similar to those found in intestinal stem cells, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have found. The team of researchers, led by ICREA researcher Eduard Batlle, propose that patients with colorectal cancer undergo genetic tests of their intestinal epithelium in...

2011-03-07 21:23:05

The intestinal epithelium consists of four main specialized cell lineages: absorptive enterocytes and three secretory cell types known as enteroendocrine, Paneth, and goblet cells. But a rare, fifth type of intestinal cell called tuft cells also exists. Defined by the thick brush of long microvilli that project from their apical surface, tuft cells are seen in several epithelial tissues, yet little is known about their function due to a lack of tuft cell"“specific markers. In the March...

2010-05-14 13:23:31

Scientists at the Stanford University School of Medicine have pushed into place another piece of the puzzle of how Listeria monocytogenes, a dangerous food-borne pathogen, slips through the intestine's defenses and causes disease. Listeria monocytogenes is a hardy, if unwelcome, brunch guest. This bacterial strain thrives in salty or cold environments where prissier pests might perish: cold cuts, smoked salmon, soft cheeses and many a refrigerator. Abundant in the environment, it seldom...

2010-05-12 11:56:31

Probiotics are a group of live microorganisms administered in adequate amounts which confer a beneficial health effect on the host. This bacterial community plays a pivotal role in human nutrition and health by promoting the supply of nutrients, preventing pathogen colonization and shaping and maintaining normal mucosal immunity. While the precise mechanistic basis of the beneficial effects of probiotics is obscure and will most likely vary depending on the strain and species used. A research...

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2008-03-24 11:15:00

Animal study reveals mechanism behind rise in salmonella bacteremia in AIDS patientsNearly half of all HIV-positive African adults who become infected with Salmonella die from what otherwise would be a seven-day bout of diarrhea. Now, UC Davis School of Medicine scientists have discovered how salmonella becomes lethal for AIDS patients. Their findings also implicate a mechanism by which HIV evades the powerful drugs used to treat AIDS."We have found the defect in the immune response that...

2005-09-20 15:05:00

PITTSBURGH -- Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells. This surprising discovery, being reported by two University of Pittsburgh School of Medicine researchers in the September issue of the journal Immunity, may explain how an immune response can be so exquisitely swift. The research not only proves cells other than neurons are capable of...


Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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