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Latest Macrophage Stories

2014-04-28 10:15:29

Inflammation has long been considered an integral part of the biological process that leads to deadly scarring in idiopathic pulmonary fibrosis. New research at National Jewish Health, however, suggests that a little inflammation may also be crucial to the healing and repair processes in the lungs.  Elizabeth Redente, PhD, assistant professor of cell biology at National Jewish Health, and her colleagues report in the April 2014 issue of the American Journal of Respiratory Cell and Molecular...

Disrupted Sleep Patterns May Accelerate Tumor Growth
2014-01-28 06:29:35

Brett Smith for redOrbit.com - Your Universe Online A new study from a team of American researchers has revealed that a disrupted sleep pattern can accelerate the progression of cancer. According to the team’s report published in the journal Cancer Research, fragmented sleep disrupts a cancer-fighting metabolic pathway – a disruption that could be mitigated through drug therapy. "It's not the tumor, it's the immune system," said study director Dr. David Gozal, chairman of...

2014-01-08 11:12:42

A well-documented suppressor of immunity that's used by fetuses and tumors alike, just may be able to change its spots, researchers report. In the face of a significant bacterial infection, for example, indoleomine 2,3-dioxegenase, or IDO, also appears capable of helping key immune cells called macrophages produce inflammation to destroy the invader, said Dr. Tracy L. McGaha, immunologist at the Medical College of Georgia at Georgia Regents University and GRU Cancer Center. The...

2014-01-03 11:31:48

Mycobacterium tuberculosis is a major cause of death worldwide, and a formidable foe. Most healthy people can defend themselves against tuberculosis, but they need all parts of their immune system to work together. A study published on January 2nd in PLOS Pathogens reveals how a special class of immune cells called "invariant natural killer T cells" make their contribution to this concerted effort. "We were interested in identifying the mechanisms that different types of T cells use to...

TB Bacteria Hide Their Identity To Invade Into Deeper Regions Of The Lungs
2013-12-20 14:30:54

University of Washington Cell surface lipids hide molecular patterns that infection-killing cells might recognize as dangerous TB-causing bacteria appear to mask their identity to avoid recognition by infection-killing cells in the upper airways. The bacteria call up more permissive white blood cells in the deeper regions of the lungs and hitch a ride inside them to get into the host's body. Details on this finding are reported Dec. 16 in the advanced online edition of the journal...

2013-12-18 13:33:05

A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S. The discovery, based on a comprehensive study in a mouse model of atherosclerosis, contradicts a long-held hypothesis about the role of iron in the disease and carries important implications for patients with chronic kidney disease or anemia related to...

2013-12-16 23:01:48

St. Jude Children’s Research Hospital scientists find mechanism that launches production of the specialized T cells essential for combating infectious agents and that offers new therapeutic possibilities Memphis, Tenn. (PRWEB) December 16, 2013 St. Jude Children’s Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the...

2013-12-16 18:10:41

Cancer cells fused with macrophages exhibit enhanced adhesive strength, formed tumors more rapidly than unfused cancer cells and flourished under conditions that dramatically inhibited growth of unfused cancer cells Cancer cells that spontaneously fuse with macrophages, the immune system's healthy scavenger cells, play a key role in the metastasis, or spread of the cancer to other areas of the body, according to research to be presented Sunday, Dec. 15, at the American Society for Cell...

Bacteria Turns Nasty When Under Threat
2013-12-15 05:21:32

Ranjini Raghunath for redOrbit.com - Your Universe Online E. coli is one of millions of bacterial species that live in our gut. From when we are infants, E. coli dwells peacefully in the lower intestine, maintaining a give-and-take relationship with our body – it helps the gut digest food, and gets energy to live and reproduce in return. However, the normally harmless bacterium can quickly evolve into a deadly form that can cause severe food poisoning, infection, and sometimes death....

2013-12-12 11:01:55

Scientists have used a new method to map the response of every salmonella gene to conditions in the human body, providing new insight into how the bacteria triggers infection. In a world first, the scientists exposed salmonella to 22 lab environments that mimic conditions that the bacterium finds when it enters the human body and discovered the effects of these conditions on individual genes in the bacteria. After people eat salmonella, the microbes enter the stomach, and intestine, and...


Latest Macrophage Reference Libraries

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2011-04-15 13:07:05

Chlamydophila psittaci is a lethal intracellular bacterial species that causes endemic avian chlamydiosis, epizootic outbreaks in mammals, and respiratory psittacosis in humans. It can be transmitted through inhalation, contact, or ingestions among birds and mammals. It generally starts with flu-like symptoms and becomes a life-threatening pneumonia. Many stay dormant until activated by stress. Birds are great vectors of the disease since they are highly mobile and feed on infected animals....

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Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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