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Latest Macrophages Stories

2014-07-16 12:39:43

Johns Hopkins Medicine Process suggests a new type of immunotherapy A team of researchers has devised a Pac-Man-style power pellet that gets normally mild-mannered cells to gobble up their undesirable neighbors. The development may point the way to therapies that enlist patients' own cells to better fend off infection and even cancer, the researchers say. A description of the work will be published July 15 in the journal Science Signaling. "Our goal is to build artificial cells...

2014-06-25 10:25:31

Ohio State University Study in mice suggests immune cells fail to activate key messenger needed for repair In the complex environment of a spinal cord injury, researchers have found that immune cells in the central nervous system of elderly mice fail to activate an important signaling pathway, dramatically lowering chances for repair after injury. These studies were the first to show that spinal cord injuries are more severe in elderly mice than in young adults, corroborating...

2013-12-11 12:57:14

They have discovered how the anti-tumor activity of immune cells can be restored The Leuven-based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth. They have also demonstrated that blocking the protein Nrp1 can restore this anti-tumor immune response. This is a first. Nrp1 may provide an important hub for the development of new therapies against cancer. Max Mazzone: "For many...

2013-11-25 16:39:32

A new kind of genetic switch can target the activities of just one type of brain cell Mysterious brain cells called microglia are starting to reveal their secrets thanks to research conducted at the Weizmann Institute of Science. Until recently, most of the glory in brain research went to neurons. For more than a century, these electrically excitable cells were believed to perform the entirety of the information processing that makes the brain such an amazing machine. In contrast, cells...

2013-11-15 10:58:29

Identifying 'sensome' of microglia could improve understanding, treatments for neurodegenerative disorders Massachusetts General Hospital (MGH) investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells – called microglia – to sense pathogenic organisms, toxins or damaged cells that require their response. Identifying these genes should lead to better understanding of the role of microglia both in normal brains and in neurodegenerative...

2013-08-12 14:16:37

The growth of deadly plaque inside the walls of arteries may not happen as scientists believed, research from the University of Toronto and Massachusetts General Hospital has found. The research also suggests a new potential target in the treatment of atherosclerosis, a leading cause of cardiovascular disease and death globally. The research team found that macrophages, white blood cells that drive atherosclerosis, replicate inside plaques. Moreover, this growth is not reliant on cells...

2013-08-12 11:28:38

Proliferation of immune cells within plaques is key mechanism, potential treatment target New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes. In a report being published online in Nature Medicine, researchers at the Massachusetts General Hospital (MGH) Center for Systems Biology re-evaluated previous assumptions regarding the role of inflammatory cells in atherosclerosis and found that the...

2013-06-14 12:27:42

-Alveolar macrophage (AM) function plays a critical role in protecting the lungs by removing particulates. -Chronic drinking causes persistent oxidative stress in the lungs, leading to impaired AM function. -A new rodent study shows that chronic drinking appears to intensify lung damage caused by particulate matter. Alveolar macrophage (AM) function plays a critical role in protecting the lungs from particulate matter inhalation by removing particulates from the airway and secreting...

Macrophages Key In Salamander Regeneration
2013-05-21 15:06:03

Brett Smith for redOrbit.com - Your Universe Online For years, scientists have considered salamanders the ℠Holy Grail´ of biological regeneration. Now, a new study in the Proceedings of the National Academy of Sciences has revealed an exciting step forward in the quest to adapt this ability for medical use in humans. Based on experiments with the tiny amphibians, researchers from the Australian Regenerative Medicine Institute at Monash University have found that elements of a...

2013-04-24 16:33:52

Researcher Johan Jakobsson and his colleagues have now published their results in Nature Communications "At present, researchers know very little about exactly how microglia work. At the same time, there is a lot of curiosity and high hopes among brain researchers that greater understanding of microglia could lead to entirely new drug development strategies for various brain diseases", says Johan Jakobsson, research group leader at the Division of Molecular Neurogenetics at Lund...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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