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Latest Major histocompatibility complex Stories

2009-08-31 09:36:30

Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cytoÂmegalovirus to shut down an antiviral defense (online August 31).Cytomegalovirus, which most people contract at some point in their lives, eludes immune system surveillance by targeting the protein MHC I. When we're sick, MHC I captures bits of viral proteins...

2009-07-27 11:11:41

Dr Amber Teacher, studying a post-doctorate at Royal Holloway, University of London, has discovered evidence that a disease may be causing a behavioral change in frogs. The research, published in the August edition of Molecular Ecology, has unearthed a surprising fact about our long-tongued friends: wild frogs in the UK may be changing their mating behavior.Dr Teacher conducted her research with colleagues from the Institute of Zoology and Queen Mary, University of London. The research...

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2009-07-06 12:40:00

 The future of organ transplantation could include microscopic beads that create "designer" immune cells to help patients tolerate their new organ, Medical College of Georgia researchers say."It's absolutely natural," says Dr. Anatolij Horuzsko, reproductive immunologist at the MCG Center for Molecular Chaperone/Radiobiology and Cancer Virology, who has used the approach successfully in mice with skin grafts.The degradable microparticles deliver the most powerful known form of HLA-G, a...

2009-06-08 14:41:27

When female tiger salamanders choose a mate, it turns out that size does matter - tail size that is - and that's not the only factor they weigh.Findings of a Purdue University study show that animals make more complex decisions about choosing mates than once thought. The results of Andrew DeWoody's study, released Monday (June 8) in the journal Molecular Ecology, refute a theory that animals use major histocompatibility complex (MHC) genes as the sole basis for mate choice. Immunologists have...

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2009-05-25 10:25:00

A Brazilian study has found that people are subconsciously more likely to choose a partner whose genetic make-up is different to their own, further cementing the adage that opposites really do attract, Reuters reported. Married couples were found to be more likely to have genetic differences in a DNA region governing the immune system than were randomly matched pairs, the researchers said. Maria da Graca Bicalho and her colleagues at the University of Parana in Brazil reported that this was...

2009-01-13 11:31:53

A study from a team of researchers led by Dr. Andrew P. Makrigiannis, Director of the Molecular Immunology Research Unit at the IRCM, has identified a new mechanism regulating interferon production. This discovery, co-authored by scientists from the International Medical Center of Japan (Tokyo), the National Cancer Institute at Frederick (Maryland) and the McGill Centre for the Study of Host Resistance, was published on December 22, 2008 in the Journal of Experimental Medicine.The...

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2008-08-13 00:05:00

A recent British study showed that women who take a contraceptive pill may also be changing their taste in men and leading them to those who are genetically less compatible. The study, reported by a team of researchers at the University of Liverpool, suggests that taking the pill can change the type of male scent they are attracted to. Researchers said the hormones in the pill may influence the way that women assess male sexual attractiveness. The pill is thought to disrupt an instinctive...

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2008-06-19 11:42:16

Researchers unravel complexity of the major histocompatibility complex in tailed amphibians Major Histocompatibility Complex (MHC) genes produce proteins that are crucial in fighting pathogen assault. Researchers from the Jagiellonian University in Krakow and from the Helmholtz Centre for Environmental Research (UFZ) characterized genetic variation and detected more than one MHC class II locus in a tailed amphibian. Unlike mammals, not much has been known until now about the immune defense of...

2005-09-21 20:41:41

San Diego -- A cluster of genes on chromosome six is the only one that plays a significant role in multiple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 130th annual meeting of the American Neurological Association in San Diego. "Our results confirm the strong role of the major histocompatibility complex genes in MS, and provides a definitive statement that no other region of the genome harbors a gene with a similar overall influence...

2005-07-28 14:20:00

A group of scientists at The Scripps Research Institute has solved a mystery that has dogged immunologists for many years: how T-cell receptors interact with their coreceptor proteins at the beginning of an immune response. T-cell receptors and coreceptor molecules are both large proteins displayed on the surface of T cells, and they play an essential role during the beginning of an immune response. T cells become activated after their T-cell receptor recognizes antigen -- small pieces of...


Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin