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Last updated on April 19, 2014 at 1:20 EDT

Latest Malignant hyperthermia Stories

2012-08-02 23:02:54

Hotline Available to Healthcare Professionals Seeking Treatment/Protocol Advice from Malignant Hyperthermia Specialist Consultants. Turlock, CA (PRWEB) August 02, 2012 The sudden unexpected death of a healthy individual undergoing minor surgery is a tragedy almost beyond comprehension in this day of modern medical miracles. Yet this still happens to patients susceptible to malignant hyperthermia (MH). To provide “in the moment” care for patients experiencing MH, the Malignant...

2012-01-11 06:35:23

(Ivanhoe Newswire) -- A young fit athlete who appears no different from the others on his football team dies suddenly during practice on a hot summer day. What could make this happen? According to new studies some physically fit young people could have a genetic mutation that makes them more sensitive to heat. Researchers led by those at Baylor College of Medicine may have identified a molecule that could reduce that threat. Dr. Susan Hamilton chair of molecular physiology and biophysics...

Experimental 'Couch Potato Pill' May Also Prevent Heat Stroke
2012-01-09 14:12:48

According to a new study in the journal Nature Medicine, an experimental treatment known as the 'couch potato pill' may also help to prevent heatstroke in people genetically predisposed to it. The pill first received its name due its ability to mimic the effects of exercise in inactive laboratory mice, eliciting much excitement in the medical community that it might eventually prove useful in activity-disinclined human patients as well. Yet new research shows that the drug, known to...

2010-12-13 21:10:37

Researchers have provided the first thorough mechanistic account of how a genetic defect leads to malignant hypothermia (MH) and central core disease (CCD), rare genetic skeletal muscle disorders. The study appears in the January issue of the Journal of General Physiology (www.jgp.org). Mutations in the type 1 ryanodine receptor (RYR1), the calcium release channel of the sarcoplasmic reticulum (SR) activated during skeletal muscle excitation-contraction (EC) coupling, give rise to CCD. One of...

2010-11-04 01:48:19

Using the Canadian Light Source synchrotron and the Stanford Synchrotron Radiation Lightsource, a team of researchers from the University of British Columbia has shed light on the ryanodine receptor, a structure within muscle cells that has been linked to life-threatening congenital heart conditions. The findings were published online today in the journal Nature. "The ryanodine receptor is a complex molecular machine within muscle cells," says Filip Van Petegem, an assistant professor in...

2010-07-06 15:45:00

LOUISVILLE, Ky., July 6 /PRNewswire/ -- US WorldMeds is proud to announce the launch of Revonto(TM) (dantrolene sodium for injection), the first patented scientific advancement in the treatment of malignant hyperthermia (MH). The time to reconstitute dantrolene sodium for injection has been dramatically reduced to approximately 20 seconds or until the solution is clear. Revonto(TM) retains the cost-savings of the original dantrolene sodium for injection product while offering a...

2009-09-28 08:18:00

PARSIPPANY, N.J., Sept. 28 /PRNewswire/ -- JHP Pharmaceuticals, LLC ("JHP") announced today that it had developed, and received approval by the FDA for Dantrium® IV (dantrolene sodium for injection), a rapidly mixing product. Dantrium® IV now reconstitutes in approximately 20 seconds, which is 4 times faster than before, saving valuable time and effort during a malignant hyperthermia (MH) emergency. Dantrium® IV, the rapidly mixing...

2005-06-14 17:21:28

A rare but potentially life-threatening inherited condition called malignant hyperthermia (MH) may strike surgical patients who receive common drugs for general anesthesia. Usually there is no outward sign of a problem before the drugs are given, but the drugs may trigger abnormal metabolic responses, such as a rapid rise in body temperature, muscle rigidity and other complications that may constitute a medical emergency. Approximately one in 10,000 persons have a susceptibility to MH; most...