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Latest Mammary gland Stories

2011-08-09 06:00:00

SAN DIEGO and WOODCLIFF LAKE, N.J., Aug. 9, 2011 /PRNewswire/ -- Arena Pharmaceuticals, Inc. (NASDAQ: ARNA) and Eisai Inc. announced today results from a Pathology Working Group's (PWG) re-adjudication of female rat mammary tumor diagnoses from a two-year rat carcinogenicity study of lorcaserin. Arena convened the PWG in response to the lorcaserin Complete Response Letter (CRL), which questioned the certainty of the female rat mammary tumor classifications. The PWG reviewed relevant...

2011-08-03 13:46:54

Era of Hope conference to feature compelling research examining benefits to daughters based on mother's diet During pregnancy, women are counseled to refrain from consuming certain types of foods, beverages and medications in order to avoid jeopardizing the health and development of the fetus. In fact, the American Pregnancy Association has a list of a dozen items they recommend expectant mothers omit from their diets. However, there are some additions, such as folic acid, that, when taken...

2011-06-30 19:19:16

PTPN23 can regulate the SRC oncoprotein; basis for a new therapeutic approach Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family called protein tyrosine phosphatases, or PTPs, that plays a fundamental role in switching cell signaling on and off. When the scientists suppressed the expression of PTPN23 in human mammary cells, they noted a cascade...

2011-06-29 06:58:59

(Ivanhoe Newswire) "“ Researchers have discovered a protein (Runx3) that is a potent suppressor of breast cancer growth. "People suggested that Runx3 might be a tumor suppressor in breast cancer because they found that it is down-regulated in a lot of breast cancer cell lines and breast cancer tissues," University of Illinois medical biochemistry professor Lin-Feng Chen, who led the study, was quoted as saying. In this study, Chen and his colleagues at Nagasaki University discovered...

2011-06-27 21:33:55

Researchers have identified a protein long known to regulate gene expression as a potent suppressor of breast cancer growth. Their study, in the journal Oncogene, is the first to demonstrate how this protein, known as Runx3, accomplishes this feat. "People suggested that Runx3 might be a tumor suppressor in breast cancer because they found that it is down-regulated in a lot of breast cancer cell lines and breast cancer tissues," said University of Illinois medical biochemistry professor...

2011-06-09 23:27:12

Whitehead Institute researchers have identified signals from breast epithelial cells that can induce those cells to transition to and maintain a mesenchymal and stem cell-like cell state that imbues both normal and cancer cells with a greater ability to migrate and self-renew. Interrupting these signals strips the cells of the migratory, invasive and self-renewal abilities used by cancer stem cells to seed new tumors. "Stem cells are important in both cancers and normal tissues. On the one...

2011-06-07 22:18:11

U.S. Department of Agriculture (USDA)-funded studies of mammary gland development in laboratory rats fed blueberries or other foods of interest may aid breast cancer research. In an early study that has paved the way to follow-up experiments, Rosalia C. M. Simmen of the Arkansas Children's Nutrition Center (ACNC) in Little Rock, Ark., has determined that several indicators of rat mammary gland health were improved in the offspring (pups) of mothers (dams) that had been fed 5 percent blueberry...

2011-03-11 17:07:40

In biology, the key to a healthy life is organization. Cells that properly organize themselves into communities live long and prosper, whereas disorganized cells can become cancerous. A study by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) of the different types of cells that make up the human breast  shows that not only do cells possess an innate ability to self-organize into communities, but these communities of different types of cells can also organize...

2011-03-07 21:34:47

Laminin, long thought to be only a structural support protein in the microenvironment of breast and other epithelial tissue, is "famous" for its cross-like shape. However, laminin is far more than just a support player with a "pretty face." Two studies led by one of the world's foremost breast cancer scientists have shown how laminin plays a central role in the development of breast cancer, the second most leading cause of cancer death among women in the United States. In one study it was...

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2011-01-25 08:06:29

By Elizabeth K. Gardner, Purdue University Purdue University researchers have reproduced portions of the female breast in a tiny slide-sized model dubbed "breast on-a-chip" that will be used to test nanomedical approaches for the detection and treatment of breast cancer. The model mimics the branching mammary duct system, where most breast cancers begin, and will serve as an "engineered organ" to study the use of nanoparticles to detect and target tumor cells within the ducts. Sophie Lelivre,...


Latest Mammary gland Reference Libraries

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2007-08-10 16:14:02

The Common House Mouse (Mus musculus), is the most numerous species of the genus Mus. It is the most common and populous mammalian species on earth, besides humans. House mice almost always live in close proximity to humans. Laboratory mice belong to strains of house mice and are some of the most important model organisms in biology and medicine. They are by far the most commonly used laboratory mammal. House mice are light brown to black, with short hair and a light belly. The ears and...

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