Latest Marburg virus Stories
Sarepta Therapeutics, Inc. Will Investigate feasibility of Delivery via Intramuscular Route FORT BELVOIR, Va., Sept. 6, 2012 /PRNewswire-USNewswire/ -- A contract to evaluate an alternative method for delivering a medical countermeasure (MCM) was awarded to Sarepta Therapeutics by the Joint Project Manager Transformational Medical Technologies (JPM-TMT). A component of the Joint Program Executive Office for Chemical and Biological Defense (JPEO-CBD), JPM-TMT has made significant...
Treatment with JPM-TMTFunded AVI-7288 Shows Significant Survival Rates Even When Administered up to Four Days Post Infection FORT BELVOIR, Va., Aug. 2, 2012 /PRNewswire-USNewswire/ -- A new study testing a drug candidate to treat Marburg virus demonstrated significant survival rates up to four days after exposure to the disease. Referred to as AVI-7288, the drug is a post-exposure prophylactic targeting the Marburg virus which may cause hemorrhagic fever, a severe,...
Lawrence LeBlond for redOrbit.com - Your Universe Online Ebola, one of the world’s deadliest viruses, has been confirmed in Uganda, where 14 people have already died from what health officials were calling a mysterious illness. The illness was not immediately described as Ebola because patients were not showing the typical signs of the lethal disease, the nation’s health minister told CNN on Sunday. After news of the virus broke, a team of health experts from the Centers for Disease...
Army scientists have demonstrated, for the first time, that antibody-based therapies can successfully protect monkeys from the deadly Ebola and Marburg viruses. In addition, the animals were fully protected even when treatment was administered two days post-infection, an accomplishment unmatched by any experimental therapy for these viruses to date. The work appears in this week's electronic edition of Proceedings of the National Academy of Sciences. The filoviruses, Ebola and Marburg,...
New virus could be the first filovirus to cause disease in bats A team of international researchers has discovered a new Ebola-like virus – Lloviu virus -- in bats from northern Spain. Lloviu virus is the first known filovirus native to Europe, they report in a study published in the journal PLOS Pathogens on Octobr 20th. The study was a collaboration among scientists at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, the Instituto...
Findings Published in Nature Could Lead to Drugs that Thwart Outbreaks BRONX, N.Y., Aug. 24, 2011 /PRNewswire-USNewswire/ -- Researchers at Albert Einstein College of Medicine of Yeshiva University have helped identify a cellular protein that is critical for infection by the deadly Ebola virus. The findings, published in today's online edition of Nature, suggest a possible strategy for blocking infection due to Ebola virus, one of the world's most lethal viruses and a potential bioterrorism...
Researchers at Albert Einstein College of Medicine of Yeshiva University have identified a cellular protein used by the deadly Ebola virus. The findings suggest a possible strategy for blocking infection caused by the Ebola virus, which is one of the world's most lethal viruses. The virus is notorious for killing up to 90 percent of the people it infects. It first emerged in 1976 in villages along the Ebola River in the Sudan and the Democratic Republic of Congo, Africa. The...
Cellular protein TIM-1 acts as a receptor for Ebola virus and Marburg virus, and an antibody that binds to TIM-1 blocks infection by both viruses; developing a human-compatible version of the antibody might provide a way to prevent initial infectionA team of researchers has identified a cellular protein that acts as a receptor for Ebola virus and Marburg virus. Furthermore, the team showed that an antibody, which binds to the receptor protein, is able to block infection by both...
Ebola, a virus that causes deadly hemorrhagic fever in humans, has no known cure or vaccine. But a new study by University of Illinois at Chicago scientists has uncovered a family of small molecules which appear to bind to the virus's outer protein coat and may inhibit its entry into human cells.The results are to be published in the Journal of Medicinal Chemistry and are now online.Previous studies have shown that small molecules can interfere with the Ebola infection process, says Duncan...
Boston University researchers develop portable diagnostic deviceBoston University researchers have developed a simple diagnostic tool that can quickly identify dangerous viruses like Ebola and Marburg. The biosensor, which is the size of a quarter and can detect viruses in a blood sample, could be used in developing nations, airports and other places where natural or man-made outbreaks could erupt."By enabling ultra-portable and fast detection, our technology can directly impact the...
Latest Marburg virus Reference Libraries
Marburg virus, or Marburg, is the standard name for the genus of viruses Marburgvirus which contains the species, Lake Victoria Marburgvirus. It causes Marburg Hemorrhagic Fever (MHF) which originated with primates. It originated in Africa and can infect humans and primates. It is in the same taxonomic family as Ebola and both are identical structurally although they elicit different antibodies. It was named after the location of the first outbreak in Marburg, Germany in 1967. The...
Filoviridae family of viruses belongs to the order of Mononegavirales. Filoviruses cause hemorrhagic fever often with fatal bleeding and coagulating abnormalities. The name comes from the Latin word filum, which alludes to the thread-like appearance of virus particles. They are single stranded negative sense RNA viruses that target primates. The two genera are Ebola-Reston virus and Marburg virus. The family was discovered in 1967 when 31 people were infected with the Marburg virus in...
Ebolavirus (EBOV), a viral genus, is the disease Ebola hemorrhagic fever (EHF), a viral hemorrhagic fever (VHF). The virus gets its name from the Ebola River Valley in the Democratic Republic of the Congo where the first outbreak occurred in 1976. The virus was obscure until 1989 when several widely publicized outbreaks occurred among monkeys in the United States. The virus disrupts the endothelial cells lining the interior surface of blood vessels. The platelets become unable to...
