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Latest Marc Lacroix Stories

2012-07-18 06:37:41

(Ivanhoe Newswire) — Investigators from the Vanderbilt Center for Bone Biology have discovered that stress can promote the colonization of breast cancer cells in bone. Mice studies revealed that the activation of the sympathetic nervous system (the "fight or flight" response) primes the bone environment for breast cancer cell metastasis. Researchers were able to prevent breast cancer cell lesions in bone using propranolol, a cardiovascular medicine that inhibits sympathetic nervous...

2012-06-14 12:22:54

An important gene for bone metastasis Breast cancer cells frequently move from their primary site and invade bone, decreasing a patient's chance of survival. This process of metastasis is complex, and factors both within the breast cancer cells and within the new bone environment play a role. In next week's Journal of Biological Chemistry "Paper of the Week," Roger Gomis and colleagues at the Institute for Research in Biomedicine in Spain investigated how breast cancer cells migrate to...

2012-04-10 10:56:42

Peroxiredoxin 2 protects tumor cells from oxidative stress and promotes their growth and proliferation in the lung Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that breast cancer cells that metastasize to the lung express a higher level of the protein peroxiredoxin 2 (PRDX2). The study suggests that the modulation of the levels of this protein could be a new therapeutic strategy to prevent lung metastases. The study results have been advanced in the...

2011-10-21 05:28:47

By: Alicia Rose DelGallo, Ivanhoe Health Correspondant (Ivanhoe Newswire) -- Cancer breakthroughs may be deceptive to the public. A study, published in the open-access journal PLoS Computational Biology on October 20, questions the reasoning used in many highly cited cancer publications supporting the relevance of animal and test tube experiments to human cancer. Due to ethical guidelines, most experimental cancer research is performed on animals or cells living in test tubes....

2011-02-14 15:26:50

A team of researchers at CIC bioGUNE has revealed that oestrogen can reduce the risk of breast cancer. Their work shows that oestrogen is capable of reducing the number of breast cancer stem cells, which may explain the lower aggression of the tumor and, as a consequence, the possibility of a better prognosis. The project was published in Breast Cancer Research and Treatment and the team will present the results under the auspices of the International Conference on Breast Cancer to be held in...

2009-11-03 15:49:47

Researchers have reduced breast cancer metastasis to bone using an experimental agent to inhibit ROCK, a protein that was found to be over-expressed in metastatic breast cancer. In a study in mice, the team of researchers from Tufts University School of Medicine, the Sackler School of Graduate Biomedical Sciences at Tufts, and Tufts Medical Center report that inhibiting ROCK, or Rho-associated kinase, in the earliest stages of breast cancer decreased metastatic tumor mass in bone by 77...

2009-10-10 10:06:17

Researchers find new tumor suppressor destroys a key link in cancer chain A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports this week in the journal Molecular Cell. "KEAP1 is a recently discovered tumor suppressor, but how it works has not been known. IKKß is a known oncoprotein that...

2009-08-04 10:56:11

A subset of tumor cells that remain after a woman with breast cancer undergoes treatment with either anti-cancer or anti-hormone therapy shows a "gene signature" that could be used to define targets for developing new drugs against the disease, said a consortium of researchers led by Baylor College of Medicine (www.bcm.edu). The report appears in the current issue of the Proceedings of the National Academy of Sciences."We have found that gene expression patterns in a subset of these resistant...

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2009-07-01 10:45:00

Previously, only a few genes had been associated with the formation of metastases in colorectal cancer. Now, researchers of the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch and Charit© "“ University Medicine Berlin, Germany, have identified 115 genes that are deregulated both in the primary tumor and in its metastases. In the future, their findings may help identify patients with aggressive tumors at an earlier stage (Gastroenterology 2009,...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.