Latest Marc Montminy Stories

2012-04-09 09:28:25

Salk researchers find molecular switch that controls liver glucose production and may represent a new avenue for treating insulin-resistant type II diabetes In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose---- the simple sugar that is the source of energy in human cells and the central player in diabetes. In a paper published April 8 in...

2011-09-27 13:03:25

Salk researchers identify cellular mechanism in the pancreas that turns on insulin production Researchers at the Salk Institute have discovered how a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin. The finding, published today in the Proceedings of the National Academy of Sciences, raises the possibility that new designer drugs might be able to turn on key molecules in this pathway to help the 80 million Americans who have type 2...

2010-12-20 08:16:06

(Ivanhoe Newswire) -- It turns out our ancient ancestors may be to blame for the obesity epidemic.  According to a research team at the Salk Institute of Biological Studies, evolutionary adaptations may have genetically shaped how our body stores and burns fat. Led by Marc Montminy, M.D., Ph.D, and professor at the Clayton Foundation Laboratories for Peptide Biology, the team studied a particular gene called CRT3, which is responsible for decreasing energy expenditure in fat cells....

2010-12-16 09:04:37

In addition to fast food, desk jobs, and inertia, there is one more thing to blame for unwanted pounds-our genome, which has apparently not caught up with the fact that we no longer live in the Stone Age. That is one conclusion drawn by researchers at the Salk Institute for Biological Studies, who recently showed that mice lacking a gene regulating energy balance are protected from weight gain, even on a high fat diet. These findings have implications for the worldwide obesity epidemic and...

2009-06-21 12:47:55

Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two. Their findings, to be published in the June 21, 2009 advance online edition of the journal Nature, explain how obesity sets the stage for diabetes and why thin people can become insulin-resistant. The Salk...

2005-09-07 16:21:31

La Jolla, CA "“ In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar levels are high. Scientists at the Salk Institute for Biological Studies discovered a key cellular switch that controls glucose production in liver cells. This switch may be a potential new target for the development of highly specific diabetes drugs that signal the liver to reduce the production of sugar. The Salk...

Word of the Day
  • Boughs or branches.
  • Warbling of birds in trees.