Latest Marfan syndrome Stories
Scientists at Johns Hopkins have shown in laboratory experiments in mice that blocking the action of a signaling protein deep inside the heart's muscle cells blunts the most serious ill effects of high blood pressure on the heart.
Johns Hopkins researchers have compiled what they believe are reliable lists of tell-tale physical signs to help doctors recognize children with Marfan and Loeys-Dietz syndromes.
ST JOSEPH, Mich., July 20, /PRNewswire/ -- GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that Dr.
Case Western Reserve researchers find deficiency of Kruppel-like Factor 15 predicts cardiovascular diseases.
By studying the genetics of a rare inherited disorder called stiff skin syndrome, researchers at the Johns Hopkins University School of Medicine have learned more about scleroderma, a condition affecting about one in 5,000 people that leads to hardening of the skin as well as other debilitating and often life-threatening problems.
The aorta, the body's largest artery, stretches from the chest to below the kidneys, expanding and contracting with the pressure of blood driven directly into it by the heart.
By Jonathan Bor, The Baltimore Sun Jun. 26--A popular blood-pressure medication has shown promise as a therapy for Marfan syndrome, slowing and, in some cases, stopping the enlargement of a major blood vessel that can lead to fatal ruptures, Johns Hopkins researchers reported today.
Scientists have identified the first genetic mutations that cause the aorta â€“ the body's main artery â€“ to widen, tear and rupture.
Marfan's syndrome is a genetic disorder of the connective tissue that causes excessively tall stature and long extremities. It is carried by the gene FBN1, which encodes the connective protein fibrillin-1, and is a dominant trait. The human genetic makeup contains a pair of FBN1 genes, so because of its dominance, inheriting one affected FBN1 gene from either parent will result in Marfan's syndrome. It effects both males and females, and has no ethnic bias. It was named after Antoine Marfan,...
- A person who stands up for something, as contrasted to a bystander who remains inactive.
- One of the upright handlebars on a traditional Inuit sled.