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Latest Mass drug administration Stories

2010-08-11 13:55:00

Current tools for combating malaria, such as artemisinin-combination therapy and increasing coverage of long-lasting insecticide bednets can result in major reductions in Plasmodium falciparum malaria transmission and the associated disease burden in Africa. Furthermore, if such interventions can be rolled out to achieve a comprehensive and sustained intervention program, a parasite prevalence threshold of 1% may be achievable in areas where there is a low- to moderate transmission of malaria...

2010-01-11 16:34:36

Researchers are a step closer to developing new antimalarial drugs after discovering the normal function of a set of proteins related to the malaria parasite protein, which causes resistance to the front-line drug chloroquine. The findings also provide a novel tool for studying the malarial chloroquine-resistance factor. The study examined transporter proteins which are known to move compounds around the cell. The genes for these proteins are present in plants as well as the malaria parasite...

2009-11-02 07:30:00

Unprecedented data from ACTwatch unveils low accessibility of ACTs ACTwatch, a research project led by PSI, in collaboration with the London School of Hygiene and Tropical Medicine, released evidence today that indicates that artemisinin combination therapy, the most effective medicines for treating malaria, continue to have a significantly low presence on the market among populations considered to be most at risk. Announcing the results at the 5th Multilateral Initiative on Malaria (MIM)...

2009-07-08 11:22:25

Current combination malaria therapies recommended by the World Health Organization (WHO) provide adequate treatment for mild malaria, according to a Cochrane Systematic Review of the evidence. However, selected trials had high failure rates for some combinations and evidence for the effectiveness of anti-malarial therapies is lacking in some vulnerable groups.Malaria kills more than a million people each year and accounts for more than a third of public health expenditure in some badly...

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2009-05-29 15:16:08

The first evidence of resistance to the world's most effective drug for treating malaria has been found by international scientists. The scientists said that the trend in western Cambodia has to be urgently contained because full-blown resistance would be a global health catastrophe. Drugs are taking longer than before to clear blood of malaria parasites. This shows early signs of emerging resistance to a disease that kills a million people each year. The most effective drug cleared all...

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2009-02-26 07:10:00

A disease once thought to be somewhat under control with the use of prescription drugs is emerging at the Thai-Cambodian border as drug resistant. The World Health Organization said Wednesday the new strain of malaria could "seriously undermine" efforts to bring the disease under control. "Surveillance systems and research studies... are providing new evidence that parasites resistant to artemisinin have emerged along the border between Cambodia and Thailand where workers walk for miles...

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2009-01-27 15:11:30

The afflictions of impoverished Cambodia can be seen in the nation's western corner:  girls for hire standing outside restaurants, uneven dirt roads dotted with signs that warn "Danger Mines!" But a potentially greater danger lurks there, particularly for the outside world. The parasite that causes the most lethal form of malaria is showing initial signs of resistance to the best new drug that treats the disease, the New York Times reports. Combination treatments using the antimalaria...

2008-09-19 15:00:08

Text of report by Nairobi-based online news service of UN regional information network IRIN on 19 September Kampala, 19 September 2008: The Ugandan government is to subsidize the most effective form of malaria treatment sold in the private sector. Although such treatment, Artemisinin Combination Therapy (ACT), is available free in public clinics, for most Ugandans, the first port of call in times of sickness is the local pharmacy. With the help of donors, the drugs will be available...

2006-07-02 13:21:18

WASHINGTON (Reuters) - An allergy drug pulled off the market in 1999 could work to treat malaria, U.S. researchers reported on Sunday. The drug is called astemizol and marketed under the brand name Hismanal by Janssen Pharmaceutica, a unit of Johnson & Johnson, and can kill the Plasmodium falciparum parasite that causes malaria. Researchers from the Johns Hopkins University Schools of Medicine and Public Health tested astemizol in test tubes and in mice. Moderate doses reduced...

2006-07-02 12:00:00

WASHINGTON (Reuters) - An allergy drug pulled off the market in 1999 could work to treat malaria, U.S. researchers reported on Sunday. The drug is called astemizol and marketed under the brand name Hismanal by Janssen Pharmaceutica, a unit of Johnson & Johnson, and can kill the Plasmodium falciparum parasite that causes malaria. Researchers from the Johns Hopkins University Schools of Medicine and Public Health tested astemizol in test tubes and in mice. Moderate doses reduced the numbers...