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Latest Mast cell Stories

Bee Sting Allergies Could Be Defense Mechanism
2013-10-25 05:04:12

[ Watch the Video: The Evolution Of An Allergy ] redOrbit Staff & Wire Reports - Your Universe Online While bee stings could be fatal to those who are allergic to the insect’s venom, that type of adverse biological reaction is actually the body’s attempt to protect a person from potentially deadly toxins. Writing in Wednesday’s edition of the journal Immunity, scientists from the Stanford University School of Medicine and their colleagues describe how they injected mice...

2012-08-03 01:21:16

TAU research identifies a protein group that may kick-start allergic reactions Allergies, or hypersensitivities of the immune system, are more common than ever before. According to the Asthma and Allergies Foundation of America, one in five Americans suffers from an allergy – from milder forms like hay fever to more severe instances, like peanut allergies which can lead to anaphylactic shock. While medications like antihistamines can treat the symptoms of an allergic reaction, the...

2011-12-02 01:52:22

Discovery provides new insights on role of histamine releasing factor in asthma and allergies La Jolla Institute for Allergy & Immunology scientists have identified the histamine releasing factor (HRF) molecule as a promising target for developing new treatments for a number of allergic reactions including asthma. The research team, led by Toshiaki Kawakami, M.D., Ph.D., is also the first to clarify the role of the HRF molecule in promoting asthma and some allergies, including...

2011-10-14 09:14:02

Researchers from the University of Notre Dame have announced a breakthrough approach to allergy treatment that inhibits food allergies, drug allergies, and asthmatic reactions without suppressing a sufferer's entire immunological system. The therapy centers on a special molecule the researchers designed, a heterobivalent ligand (HBL), which when introduced into a person's bloodstream can, in essence, out-compete allergens like egg or peanut proteins in their race to attach to mast cells, a...

2011-07-02 02:40:46

Stanford University School of Medicine investigators have linked a master molecule of the immune system, gamma-interferon, to the pathology of asthma, in a study of mice. This somewhat surprising finding "” the key immune molecule has often been assumed to steer the immune system in a different direction from the cluster of allergic disorders to which asthma belongs "” could lead to new treatments for the disease. Gamma interferon's role in asthma has been fuzzy. High levels of...

2011-02-25 19:18:52

Heparin plays a key role in allergic and inflammatory reactions driven by mast cells, scientists from Karolinska Institutet in Sweden shows in an international collaboration involving colleagues from Germany and Switzerland. The study is published in the recent issue of Immunity, and sheds some new light on the biological function of heparin. Heparin has a long history at Karolinska Institutet, since here the substance was originally purified and its chemical structure was characterized back...

2009-05-01 08:27:32

If you're one of the millions who dread the spring allergy season, things are looking up. A research study appearing in the May 2009 issue of the Journal of Leukocyte Biology (http://www.jleukbio.org) shows how a team of American scientists have identified a previously unknown cellular switch that turns allergies and asthma both on and off. Equally important, this study also suggests that at least for some people with asthma and allergies, their problems might be caused by genes that prevent...

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2008-01-14 10:15:55

Findings point to calcium channels as essential regulators of mast cell activation.BOSTON "“In demonstrating that a group of calcium ion channels play a crucial role in triggering inflammatory responses, researchers at Beth Israel Deaconess Medical Center (BIDMC) have not only solved a longstanding molecular mystery regarding the onset of asthma and allergy symptoms, but have also provided a fundamental discovery regarding the functioning of mast cells. Their findings appear in the...

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2006-09-08 12:30:00

The body's mast cells are mainly associated with allergic reaction in the way they release histamine and other inflammatory substances. However, researchers at Karolinska Institutet have now demonstrated how the mast cells can also contribute to diseases like psoriasis and cancer. Mast cells are most known for their association with allergic reactions, as they act like microscopic "bombs" to trigger the release of a number of substances that give rise to the classic allergic symptoms, such as...

2005-08-25 11:37:15

RICHMOND, Va. (Aug. 24, 2005) "“ Virginia Commonwealth University immunologists studying mast cells, known to play a central role in asthma and allergic disease, have identified a hormone-like molecule that can kill these cells by programming them to die in studies with mice. The findings move researchers another step closer to understanding the life cycle of mast cells, and may help researchers develop new treatments for allergy and inflammatory responses in arthritis, multiple...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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