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A molecule responsible for the proper formation and function of neurons finds its way to the right place not because it is actively recruited, but because it can't go anywhere else. Researchers at Baylor College of Medicine have identified a distal axonal cytoskeleton that functions as a boundary to ensure a key scaffolding protein, called ankyrinG, stays at the start of the axon near the cell body where it performs its functions of clustering sodium and potassium ion channels and...
A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere else. Researchers at Baylor College of Medicine have identified a distal axonal cytoskeleton as the boundary that makes sure AnkyrinG clusters where it needs to so it can perform properly. "It has been known that AnkyrinG is needed for the axon initial segment to form. Without the axon...
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