Latest MECP2 Stories

2006-07-06 15:42:24

WASHINGTON (Reuters) - A gene mutation that shrinks brain cells may be responsible for the mental retardation of Down's syndrome, U.S. researchers reported on Wednesday. The finding suggests there may be a way to interfere with or even reverse the additional mental decline often seen as people with Down's syndrome age. The finding, published in the journal Neuron, also may apply to Alzheimer's disease, the researchers said. "If we can decrease the expression of this gene we may be...

2005-09-02 16:11:19

Adrian Bird of the University of Edinburgh and colleagues report today in the online issue of Molecular Cell that the "Rett Syndrome protein", MeCP2, only binds to genes with a specific sequence of nucleotide bases. This knowledge will aid in the identification of the genes that are regulated by the gene MECP2. This work was supported, in part, by the Rett Syndrome Research Foundation (RSRF). Rett Syndrome (RTT) is a severe neurological disorder diagnosed almost exclusively in girls....

2005-08-23 13:41:40

Sacha Nelson of Brandeis University in Waltham, MA and Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA and their colleagues report online today in the Proceedings of the National Academy of Sciences Early Edition that spontaneous neuronal activity is reduced in the cortex of a knockout mouse model for the childhood neurodevelopmental disorder, Rett Syndrome. The Rett Syndrome Research Foundation (RSRF) and the McKnight Foundation funded this project. Rett...

Word of the Day
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'karpos', fruit.