Latest MED12 Stories

2011-08-25 21:29:09

Uterine leiomyomas, also called fibroids, cause a very significant burden to women's health. They are benign tumors that occur in 60% of women by the age of 45 years and cause symptoms such as abdominal pain and discomfort, and abnormal bleeding, in about half of the cases. Fibroids are also an important cause of infertility. These tumors are the most common medical reason for hysterectomy. Considering the clinical importance of fibroids, relatively little has been known about the...

2008-08-12 00:00:43

U.S. researchers said they've found a clue to understanding the biology of gene-linked mental retardation. The University of Texas Health Science Center researchers said they've discovered the mechanism by which the protein MED12 ensures correct neuronal gene expression. Mutations associated with X-linked mental retardation are known to disrupt the function of the protein. "We found that MED12 directs a histone-modifying enzyme to mark neuronal genes with a repressive signal and, further,...

Word of the Day
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.