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Latest Medulloblastoma Stories

2012-02-15 23:07:00

    Medulloblastoma is the most common malignant brain tumor in children.     Disseminated medulloblastoma is particularly lethal and requires extensive radiation therapy to the brain, which can cause brain damage.     An oncolytic measles virus has shown effectiveness in a new model of disseminated human medulloblastoma. A strain of measles virus engineered to kill cancer cells prolongs survival in a model of medulloblastoma that is...

2012-02-13 23:05:58

Sanford-Burnham researchers create a new mouse model for a particularly malignant form of medulloblastoma, and zero in on a potential therapy Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) developed a new mouse model for studying a devastating childhood brain cancer called medulloblastoma. The animal model mimics the deadliest of four subtypes of human medulloblastoma, a tumor that is triggered by elevated levels of a gene known as Myc. The study, published...

2011-09-28 05:54:16

(Ivanhoe Newswire) -- Medulloblastomas are the most common cancerous brain tumors in children. Although survival rates have improved over the years, medulloblastoma remains associated with substantial mortality, and long-term survivors often suffer debilitating effects from the intensive treatments. A team of researchers, led by Cecilia Söderberg-Nauclér and John Inge Johnsen, at the Karolinska Institutet, Sweden, has now identified a potential target for a more...

2011-09-27 09:26:51

Medulloblastomas are the most common cancerous (malignant) brain tumors in children. Although survival rates have improved over the years, medulloblastoma remains associated with substantial mortality, and long-term survivors often suffer debilitating effects from the intensive treatments. A team of researchers, led by Cecilia Söderberg-Nauclér and John Inge Johnsen, at the Karolinska Institutet, Sweden, has now identified a potential target for a more...

2011-09-23 21:35:00

Family Abstract, Inc. is a proud supporter of Wylie's Day and The Children's Hospital Of Pennsylvania. Family Abstract, Inc. continues to participate, in the walk/run with the hope that one day we can rid the world of Pediatric Brain Tumors. Horsham, PA (PRWEB) September 23, 2011 Family Abstract Inc., a real estate title insurance company in Horsham, PA, is again this year helping promote the CHOP (Childrenâs Hospital of Philadelphia) Four Seasons Parkway Run and to support the...

2011-09-19 22:14:15

Regulatory protein represents potential drug target Medulloblastomas constitute the most frequent class of malignant childhood brain tumor. Tumors of this type arise due to the uncontrolled proliferation of immature nerve cells in the developing brain, and there is no targeted treatment available. A research team based at LMU℠s Center for Neuropathology and Prion Research and led by Privatdozent Dr. Ulrich Schüller has now demonstrated that the regulatory protein FoxM1...

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2011-01-08 11:30:00

Scientists have identified the type of cell that is at the origin of brain tumors known as oligodendrogliomas, which are a type of glioma "“ a category that defines the most common type of malignant brain tumor.In a paper published in the December 2010 issue of the journal Cancer Cell, investigators found that the tumor originates in and spreads through cells known as glial progenitor cells "“ cells that are often referred to as "daughter" cells of stem cells. The work comes at a...

2010-12-31 12:21:46

(Ivanhoe Newswire) "“ Medulloblastoma, the most common pediatric brain cancer and leading killer of children with cancer, has been genetically decoded by scientists at the Johns Hopkins Kimmel Cancer Center. The genetic "map" is believed to be the first reported of a pediatric cancer genome. The findings show that children with medulloblastoma have five- to tenfold fewer cancer-linked alterations in their genomes compared with their adult counterparts."These analyses clearly show that...

2010-12-23 02:11:54

Arsenic is usually thought of as a poison. Despite this, it has been used in medicine for over 2000 years, and the arsenic compound arsenic trioxide (ATO) is FDA approved for the treatment of acute promyelocytic leukemia. Now, a team of researchers, led by Aykut Ãœren, at Georgetown University Medical Center, Washington, has generated data using human cancer cell lines that suggest that ATO might also be of benefit to individuals with certain brain tumors or...

2010-12-23 02:10:08

The drug is already FDA-approved for one kind of cancer. Researchers say immediate clinical applications to treat other cancers is possible Researchers at the Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, have found that an arsenic-based agent already FDA-approved for a type of leukemia may be helpful in another hard-to-treat cancer, Ewing's Sarcoma (ES). The research, based on animal studies, also suggests the drug might be beneficial in...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'