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Latest Medulloblastoma Stories

2009-09-02 23:50:00

The Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. One patient with the most common type of pediatric brain cancer, medulloblastoma, also showed tumor shrinkage. Initial results of the drug trial, conducted at Johns Hopkins (Baltimore), the Karmanos Cancer Center (Detroit) and the Translational Genomics Research Institute...

2009-03-10 14:19:07

A discovery in Canada could help more children survive brain cancer. Research funded by the Canadian Cancer Society discovered eight similar genes that when mutated, appear to be responsible for medulloblastoma, the most common form of childhood brain cancers. Researchers learned when the eight genes are functioning normally it appears their role is to make proteins that tell the developing brain when to stop growing. They said when the genes are mutated the brain may continue to grow out of...

2009-03-09 13:13:02

Canadian scientists say they've discovered eight similar genes that, when mutated, appear to cause medulloblastoma -- a common childhood brain cancer. This discovery is very promising and may help researchers develop better, more targeted treatments so that more of these children will survive and fewer will suffer debilitating side effects, said Christine Williams, director of research programs for the Canadian Cancer Society Research Institute. The study was led by Dr. Michael Taylor, a...

2009-03-09 07:42:26

May lead to better drug treatments Researchers funded by the Canadian Cancer Society have discovered eight similar genes that, when mutated, appear to be responsible for medulloblastoma "“ the most common of childhood brain cancers. The findings are published yesterday in the online edition of the journal Nature Genetics. "This discovery is very promising and may help researchers develop better, more targeted treatments so that more of these children will survive and fewer will suffer...

2008-09-07 03:00:07

By Valle, Luis Del White, Martyn K; Khalili, Kamel Abstract The human polyomavirus JC (JCV) is a small DNA tumor virus and the etiologic agent of the progressive multifocal leukoencephalopathy. In progressive multifocal leukoencephalopathy, active JCV replication causes the lytic destruction of oligodendrocytes. The normal immune system prevents JCV replication and suppresses the virus into a state of latency so that expression of viral proteins cannot be detected. In a cellular context...

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2008-03-24 11:05:00

M. D. Anderson team connects REST to regenerative medicine, pediatric brain cancerA protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature. Researchers show RE1-silencing transcription factor (REST) plays a dual role in embryonic stem cells, said senior author Sadhan...

2007-02-14 09:00:00

By Takei, Hidehiro; Bhattacharjee, Meenakshi B; Rivera, Andreana; Dancer, Yeongju; Powell, Suzanne Z * Context.-Immunohistochemistry (IHC) has become an important tool in the diagnosis of brain tumors. Objective.-To review the latest advances in IHC in the diagnostic neuro-oncologic pathology. Data Sources.-Original research and review articles and the authors' personal experiences. Data Synthesis.-We review the features of new, useful or potentially applicable marker antibodies as well...

2006-08-03 12:32:56

By Megan Rauscher NEW YORK (Reuters Health) - Findings from a new study suggest that a father's exposure to heat -- saunas, for example -- just before his partner becomes pregnant may increase the risk of brain tumors occurring in their offspring. "The most important thing about the findings is that they are very preliminary," Dr. Greta R. Bunin from Children's Hospital of Philadelphia told Reuters Health. "The effect on offspring of heat levels similar to saunas and hot tubs that...

2006-01-09 18:17:28

By David Douglas NEW YORK (Reuters Health) - Hearing loss appears to be a significant and under-reported side effect of platinum-based drugs used to treat a variety of childhood cancers, according to researchers. As senior investigator Dr. Edward A. Neuwelt told Reuters Health, so-called "mild" hearing loss "has major impact on academic and social development in kids, is very common after platinum chemotherapy, and may be prevented using" drugs called "thiol oto-protectants" that do...

2005-12-19 14:36:26

By Will Boggs, MD NEW YORK (Reuters Health) - Hearing loss may be more common than previously reported in children with cancer who have undergone chemotherapy with highly effective platinum-type drugs such as cisplatin and carboplatin, researchers report. "As pediatric patients experience improved survival, the effect and implications of high-frequency hearing loss with regard to academic achievement and speech and language development are important considerations, especially in...


Word of the Day
negawatt
  • A unit of saved energy.
Coined by Amory Lovins, chairman of the Rocky Mountain Institute as a contraction of negative watt on the model of similar compounds like megawatt.