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Latest Melioidosis Stories

2011-11-11 01:21:37

A key mechanism by which a bacterial pathogen causes the deadly tropical disease melioidosis has been discovered by an international team of scientists. The findings are published today in the journal Science and show how a toxin produced by the bacterium Burkholderia pseudomallei kills cells by preventing protein synthesis. The study, led by the University of Sheffield, paves the way for the development of novel therapies to combat the bacterium which infects millions of people across...

2011-10-03 22:55:33

Researchers in South East Asia have identified a novel mechanism whereby the organism Burkholderia pseudomallei — the cause of melioidosis, a neglected tropical infectious disease — develops resistance to ceftazidime, the standard antibiotic treatment. The change also makes the drug-resistant bacterium difficult to detect. B. pseudomallei is found in water and soil predominately in tropical climates and especially in South East Asia. It can infect both humans and animals and...

2010-09-15 08:00:00

CHICAGO, Sept. 15 /PRNewswire/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today participated in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference is being held in Boston, Massachusetts this week. (Logo:...

2010-08-17 08:00:00

CHICAGO, Aug. 17 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today announced that the Company will participate in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference will be held in Boston,...

2010-04-21 07:00:00

CHICAGO, April 21 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS) today announced positive results from an in vitro study assessing the efficacy of Restanza(TM) (cethromycin), its novel oral antibiotic, against 30 strains of Burkholderia pseudomallei, a serious, life-threatening bacterial pathogen. Restanza showed significant in vitro activity against clinical and environmental strains of B. pseudomallei as measured by minimal inhibitory...

2009-01-21 14:56:51

Australian scientists say they've discovered the pathogenic soil bacterium Burkholderia pseudomallei is influenced by land management practices. Researchers at the Menzies School of Health Research in Darwin, Australia, said they found the bacterium, which causes the emerging infectious disease melioidosis in humans and animals, is associated with land management changes such as livestock husbandry or residential gardening. These findings raise concerns that B. pseudomallei may spread due to...

2009-01-21 09:14:57

Researchers from Menzies School of Health Research in Darwin, Australia have found that the soil bacterium Burkholderia pseudomallei, which causes the emerging infectious disease melioidosis in humans and animals, is associated with land management changes such as livestock husbandry or residential gardening. The study, published January 20 in the open-access journal PLoS Neglected Tropical Diseases, sheds light on the environmental occurrence of this bacterium in the soil.B. pseudomallei...

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2008-10-28 10:05:00

Dutch researcher Joost Wiersinga from AMC Medical Centre in Amsterdam has unravelled a genetic defence mechanism against the lethal bacteria Burkholderia pseudomallei. The research is the next step towards a vaccine against this bacterium suitable for bioweapons.Humans have an innate defence system against deadly bacteria. However, how the step from gene to anti-bacterial effect occurs in the body is not yet known. To date, B. Pseudomallei, a bacterium suitable for bioweapons, had managed to...

2006-08-17 19:41:32

NEW YORK (Reuters Health) - Two cases of melioidosis, an infectious disease caused by the bacterium Burkholderia pseudomallei that is rare in the US, were reported to the Florida Department of Health in 2005. Both patients had recently visited or arrived from Honduras, where the disease is endemic. One case resulted in paraplegia, and the other in death. In the CDC's Morbidity and Mortality Report for August 18, Dr. Aaron Kite-Powell, from the Broward County Health Department in...

2004-11-28 03:00:22

On July 26, 2003, the Los Angeles County Department of Health Services (LACDHS) received a report that a local clinical laboratory had isolated from specimens Burkholderia pseudomallei, a category B biologic terrorism agent and the causative organism for melioidosis, which is endemic to certain tropical areas. Because laboratory workers had manipulated cultures of the organism, CDC was asked to assist in the subsequent investigation. This report summarizes the results of that investigation,...


Latest Melioidosis Reference Libraries

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2011-04-14 16:11:25

Burkholderia pseudomallei is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It causes the disease melioidosis in humans and animals and is also capable of infecting plants. The bacteria can from in a number of artificial environments. Optimal temperature is around 40°C in pH-neutral or slightly acidic environments. Most strains can ferment sugars without gas formation. The bacteria produces both exo and endo toxins although the role of these toxins has not been fully...

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Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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