Latest Membrane biology Stories

Jonny Bowden, aka “The Rogue Nutritionist”, named 8 myths surrounding cholesterol. In a recently published article on health website Natural Health Sherpa Jonny Bowden summarized these 8 myths. Wilmington, NC (PRWEB) January 27, 2013 Jonny Bowden, aka “The Rogue Nutritionist” and author of The Great Cholesterol Myth summarized the 8 myths around cholesterol in a recently published article on health website Natural Health Sherpa. In the article, Jonny Bowden clarified that high...

April Flowers for redOrbit.com - Your Universe Online A group of researchers from Brown University have demonstrated that certain skin cells use a light-sensitive receptor found outside of the eye to detect ultraviolet light and quickly begin producing melanin to prevent DNA damage. The same team, in a new study published in Proceedings of the National Academy of Sciences, has identified a key player in that biomolecular chain of events that could become a pharmacological target for...

SEATTLE, Jan. 16, 2013 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today announced that its proprietary Cellular Redistribution Assay (CRA) technology, which to date has successfully "unlocked" 46 of the 80 total Class A orphan G Protein-Coupled Receptors (GPCRs) for drug development, has identified small molecules that interact with a Class B GPCR. Like the Class A GPCRs, Class B receptors are important players in a broad range of disorders, having been linked to various...

WELWYN GARDEN CITY, England and BOSTON, January 7, 2013 /PRNewswire/ -- Heptares Therapeutics, the leading GPCR drug discovery and development company, today announced they have signed an agreement with Cubist Pharmaceuticals, Inc. (Nasdaq: CBST) to collaborate on the research and discovery of new medicines targeting G protein-coupled receptors (GPCRs), which are membrane proteins involved in a broad range of biological processes and diseases. Under the terms of the...

Discovery points to roles of diaphragms in the maintenance of blood plasma composition and survival: -PV1 expression in vascular endothelium is required for survival -PV1 is required for the formation of stomatal and fenestral diaphragms -Lack of diaphragms in fenestrated endothelia causes vascular leak of plasma proteins -Vascular leak results in severe hypoproteinemia and hypertriglyceridemia Dartmouth scientists have demonstrated the importance of the gene Plvap and the structures...

WELWYN GARDEN CITY, England and BOSTON, November 30, 2012 /PRNewswire/ -- Heptares Therapeutics, the leading GPCR drug discovery company, is delighted to announce that its Chief Scientific Officer and founder, Fiona Marshall, has received a 2012 Women of Outstanding Achievement Award from WISE, a UK national campaign to promote female talent in science, engineering, technology and the built environment. Dr Marshall received the award in the Innovation and Entrepreneurship...

WELWYN GARDEN CITY, England and BOSTON, November 29, 2012 /PRNewswire/ -- Consortium supported with over EUR20 million funding from EU Innovative Medicines Initiative and big pharma Heptares Therapeutics, the leading GPCR drug discovery company, is joining a group of leading European academic and industry researchers known as the 'K4DD' ('Kinetics for Drug Discovery') Consortium to investigate binding kinetics or 'kinotypic'...

Technische Universitaet Muenchen Nanotech structures mimic nature's way of tunneling through cell walls As reported in the journal Science, physicists at the Technische Universitaet Muenchen (TUM) and the University of Michigan have shown that synthetic membrane channels can be constructed through "DNA nanotechnology." This technique employs DNA molecules as programmable building materials for custom-designed, self-assembling, nanometer-scale structures. The researchers present evidence...

SEATTLE, Nov. 15, 2012 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today announced that GPR17-targeting compounds, which were previously identified by Omeros in connection with unlocking this orphan receptor, have now been demonstrated to promote differentiation of the cells that form myelin in the central nervous system. Myelin is critical for the proper functioning of the nervous system, and demyelination is associated with multiple nervous system disorders, including...

WELWYN GARDEN CITY, England and BOSTON, November 8, 2012 /PRNewswire/ -- Heptares Therapeutics, the leading GPCR drug discovery company, announces that its Chief Executive Officer, Malcolm Weir, will present the Company at BIO-Europe 2012 [http://www.ebdgroup.com/bioeurope/index.php ], the international partnering conference, which takes place at the CCH Congress Center, Hamburg, Germany (12-14 November 2012). Dr Weir's presentation will be at 2:15pm (CET)on...