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Latest Membrane protein Stories

2014-07-11 10:29:58

Ohio State University Scientists identify protein in bacteria with essential role in survival Scientists have identified a protein that is essential to the survival of E. coli bacteria, and consider the protein a potential new target for antibiotics. In the study, the researchers confirmed that this protein, called MurJ, flips a fatty molecule from one side of a bacterial cell membrane to the other. If that molecule isn't flipped, the cell cannot construct a critical layer that...

2014-06-09 10:48:48

Brookhaven National Laboratory Structure of membrane protein that plays a role in signaling cell death could be new target for anticancer drugs Sometimes a cell has to die—when it's done with its job or inflicted with injury that could otherwise harm an organism. Conversely, cells that refuse to die when expected can lead to cancer. So scientists interested in fighting cancer have been keenly interested in learning the details of "programmed cell death." They want to understand what...

2014-02-15 23:03:30

The Protein Society, the only international society devoted to furthering research aimed at understanding proteins, announces the winners of The 2014 Protein Society Awards. Baltimore, MD (PRWEB) February 15, 2014 The Protein Society, the only international society devoted to furthering research aimed at understanding proteins, announces the winners of The 2014 Protein Society Awards. The awards will be conferred at the 28th Annual Symposium of The Protein Society (July 27-30, 2014, San...

2013-12-18 11:24:32

Innovation could lead to faster drug therapies and increased understanding of proteins on the microscopic level Membrane proteins are the “gatekeepers” that allow information and molecules to pass into and out of a cell. Until recently, the microscopic study of these complex proteins has been restricted due to limitations of “force microscopes” that are available to researchers and the one-dimensional results these microscopes reveal. Now, researchers at the University of Missouri...

2013-12-02 21:15:20

Scientists have described a new family of proteins that appear to play a key role in cancer and might be targets for future cancer drugs. A major new study in the journal Nature sets out the structure of the new family, called glutamate intramembrane proteases – the founding member of which plays a critical role in transforming healthy cells into cancer cells. The research, funded by Cancer Research UK and conducted by scientists at The Institute of Cancer Research, London, defined...

Scientists Show X-ray Laser Can Solve Protein Structures From Scratch
2013-11-25 10:17:33

DOE/SLAC National Accelerator Laboratory SLAC's linac coherent light source reaches key milestone in decoding biological structures that were out of reach A study shows for the first time that X-ray lasers can be used to generate a complete 3-D model of a protein without any prior knowledge of its structure. An international team of researchers working at the Department of Energy's (DOE) SLAC National Accelerator Laboratory produced from scratch an accurate model of lysozyme, a...

2013-10-24 10:26:37

Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine (BUSM) and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made. These findings are published as a Letter in Nature (Park, E. et al. 2013)....

2013-10-01 15:24:08

Membrane proteins are responsible for transporting chemicals and messages between a cell and its environment. But determining their structure has proved challenging for scientists. A study by UC Santa Barbara's Han Research Group demonstrates a new tool to resolve the structure of membrane-embedded and membrane-associating proteins using the water dynamics gradient they found across and above the lipid bilayer as a unique ruler. More than 25 percent of all human proteins are membrane...

2013-09-30 14:10:50

The outer membrane of bacteria contains many proteins that form tiny pores. They are important for absorbing nutrients and transmitting signals into the cell. The research group of Sebastian Hiller, Professor of Structural Biology at the Biozentrum, University of Basel, has now shown for the first time at atomic resolution, that these pore proteins are transported in an unstructured, constantly changing state to the outer bacterial membrane. This landmark study was recently published in the...

2013-07-08 12:09:26

UConn researchers shed new light on how cellular transport systems harness energy to perform their work inside the cell Using highly sensitive fluorescent probes, a team of scientists from the University of Connecticut has captured the never-before-seen structural dynamics of an important protein channel inside the cell's primary power plant – the mitochondrion. The UConn team's study found that the channel complex - known as the translocase of the inner mitochondrial...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.