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Latest Membrane protein Stories

2011-06-30 00:35:01

- Technology earns a spot as one of the twelve finalists in the Asian Innovation Awards 2011 organised by the Wall Street Journal AsiaSingapore, June 30, 2011 - (ACN Newswire) - Synthetic cell membranes invented at the Institute of Materials Research and Engineering (IMRE), a research institute of Singapore's Agency for Science, Technology and Research (A*STAR), may improve the way we identify and develop drugs by speeding up and reducing the cost of the drug screening process.The technology...

2011-06-24 12:08:30

The ability to identify self and non-self enables cells in more sophisticated animals to ward off invading infections, but it is critical to even simpler organisms such as the social amoebae Dictyostelium discoideum. Dictyostelium exists as a single cell when times are good, but when starved, the cells aggregate and become multi-cellular fruiting bodies with a dead stalk and live spores that allow the cells to survive and pass on genes. When the social amoeba aggregates, it prefers to do so...

2011-06-23 22:54:06

The ability to identify self and non-self enables cells in more sophisticated animals to ward off invading infections, but it is critical to even simpler organisms such as the social amoebae Dictyostelium discoideum. Dictyostelium exists as a single cell when times are good, but when starved, the cells aggregate and become multi-cellular fruiting bodies with a dead stalk and live spores that allow the cells to survive and pass on genes. When the social amoeba aggregates, it prefers to do so...

2011-04-18 13:05:01

In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome "“ the cell's protein-building machinery "“ to insert a growing protein into the cellular membrane. The first study, in Nature Structural and Molecular Biology, gives an atom-by-atom snapshot of a pivotal stage in the insertion process: the moment just after the ribosome docks to a channel in the membrane and the newly forming protein winds...

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2011-03-15 11:49:48

By David Salisbury, Vanderbilt University A new laser technique has demonstrated it can measure the interactions between proteins tangled in a cell's membrane and a variety of other biological molecules. These extremely difficult measurements can aid the process of drug discovery. Scientists estimate that about 30 percent of the 7,000 proteins in a human cell reside in the cell's membrane, and that these membrane proteins initiate 60 to 70 percent of the signals that control the operation of...

2010-11-26 07:30:00

BUFFALO, N.Y., Nov. 26, 2010 /PRNewswire/ -- Dr. Michael G. Malkowski, Hauptman-Woodward senior research scientist, has received a $6.7 million grant from the National Institutes of Health in support of his work to establish the Membrane Protein Structural Biology Consortium (mpsbc.org) as one of nine centers in the United States responsible for determining membrane protein structures within a larger NIH biology-based initiative. Why is this important? The grant entitled Multi-Level...

2010-11-09 20:49:27

Nanopore array allows simultanous tests in search for new drugs Membrane-associated receptors, channels and transporters are among the most important drug targets for the pharmaceutical industry. The search for new drugs resembles looking for a needle in a haystack. Therefore new analytical techniques are required which facilitate the simultaneous screening of a large library of compounds across a variety of membrane proteins. However, this class of methods is still at the early stages of...

2010-11-01 15:21:02

They are the portals to the cell, gateways through which critical signals and chemicals are exchanged between living cells and their environments. But these gateways -- proteins that span the cell membrane and connect the world outside the cell to its vital inner workings "“ remain, for the most part, black boxes with little known about their structures and how they work. They are of intense interest to scientists as they are the targets on which many drugs act, but are notoriously...

2010-10-28 13:43:35

Membrane proteins are of immense biological and pharmaceutical importance. But so far there are only a handful of cases in which the exact structure could be successfully determined. Scientists at Columbia University, New York, and Technische Universitaet Muenchen (TUM) have now succeeded in working out the structure of an important ion channel via the analysis of related proteins. The current issue of the journal Nature reports on their findings. Proteins are molecular machines that...

2010-10-19 17:00:25

US, Argentinean scientists: Bacteria respond indirectly to cold Some bacteria react to the cold by subtly changing the chemistry of their outer wall so that it remains pliable as temperatures drop. Scientists identified a key protein in this response mechanism a few years ago, but the question of how bacteria sense cold in the first place remained a mystery. Based on a study by scientists at Rice University and Argentina's National University of Rosario, the answer is: They use a measuring...


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  • The ragged surface of a lava-flow.
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