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Last updated on April 17, 2014 at 16:09 EDT

Latest Membrane receptor Stories

2012-01-10 07:00:00

SAN DIEGO, Jan. 10, 2012 /PRNewswire/ -- Receptos Inc. today announced the successful achievement of the technology transfer milestone under its license and technology transfer deal with Janssen Pharmaceuticals, Inc. (formerly Ortho-McNeil Janssen Pharmaceuticals, Inc.), for Receptos' breakthrough GPCR crystal structure determination technology. The relationship between Janssen Pharmaceuticals and Receptos, established in December 2010, enabled Janssen with the Receptos proprietary...

2011-12-12 19:00:00

SAN DIEGO, Dec. 12, 2011 /PRNewswire/ -- Receptos Inc. announced today the establishment of a collaboration with Ono Pharmaceutical Co., Ltd. (Osaka, Japan) for the research and development of small molecule modulators of an undisclosed G-protein coupled receptor (GPCR) target. Under the terms of the agreement, Receptos will use its proprietary technology platform to produce high resolution protein crystal structures of the discovery target and drive Ono's structure-based drug...

2011-09-06 22:51:08

Findings show how form controls function in sought-after therapeutic target In a joint study, scientists from the California and Florida campuses of The Scripps Research Institute have shown that changes in a protein's structure can change its signaling function and they have pinpointed the precise regions where those changes take place. The new findings could help provide a much clearer picture of potential drugs that would be both effective and highly specific in their biological...

2011-08-04 12:30:00

SAN DIEGO, Aug. 4, 2011 /PRNewswire/ -- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD) announced today the publication of research that uncovered a previously unknown role for a class of molecules that could lead to future advances in immunologic medicine. The findings show a definitive link between EBI2, a G-protein-coupled receptor that controls B-cell migration, and some unexpected immunological effects of certain oxysterols. Co-authored by the...

2011-02-07 14:34:55

Unprecedented single molecule imaging movies of living cell membranes, taken by a research team based at Kyoto University and the University of New Mexico, have clarified a decades-old enigma surrounding receptor molecule behaviors. The results, appearing in the latest issue of the Journal of Cell Biology, promise to open the door to new possibilities for drug development. The work focuses on G protein-coupled receptors (GPCRs), a class of molecules in cell membranes that comprise the largest...

2010-05-04 06:30:00

CRANBURY, N.J., May 4 /PRNewswire/ -- Palatin Technologies, Inc. (NYSE Amex: PTN) announced that the U.S. Patent and Trademark Office issued U.S. Patent No. 7,709,484, titled "Substituted Melanocortin Receptor-Specific Piperazine Compounds," today. The claims in the issued patent relate to small molecule compounds which bind to melanocortin receptors. Palatin has received Notices of Allowance from the U.S. Patent and Trademark Office on four additional patent applications relating to...

2010-01-07 13:41:43

Researchers at the Stanford University School of Medicine have taken an early step toward identifying a new approach to drug discovery that may eventually yield drugs with fewer side effects. In a study to be published online Jan. 7 in Nature, investigators led by senior author Brian Kobilka, MD, professor and chair of molecular and cellular physiology, found that largely neglected regions on key cell-surface proteins undergo minute changes in shape in response to drugs and thus could prove...

2009-06-09 09:45:00

Uniting Technologies from Multiple Fields, Strengthening the Molecular Bioassays Market MOUNTAIN VIEW, Calif., June 9 /PRNewswire/ -- Based on its recent analysis of the molecular bioassays market, Frost & Sullivan recognizes Cisbio Bioassays with the 2009 Frost & Sullivan North America Technology Innovation of the Year Award. Its innovative, pioneering Tag-lite(TM) technology for cell surface receptor investigation, in particular G protein coupled receptors (GPCRs), brings together...

2009-04-06 16:17:59

Nicotine isn't just addictive, it may also interfere with dozens of cellular interactions in the body, U.S. researchers suggest. Brown University researchers say the data could help scientists develop better treatments for various diseases. It opens several new lines of investigation, lead author Edward Hawrot says in a statement. Hawrot and a team that included graduate students William Brucker and Joao Paulo looked specifically at the alpha-7 nicotinic acetylcholine receptor in mouse brain...