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Latest Merkel cell polyomavirus Stories

2014-07-29 04:22:01

ROCKLAND, Massachusetts, July 29, 2014 /PRNewswire/ -- - First patient begins treatment in an international Phase II study investigating the efficacy and safety of MSB0010718C in patients with metastatic Merkel cell carcinoma (mMCC) - mMCC is a rare and aggressive skin cancer lacking effective treatments - MSB0010718C is also currently being explored in a seven cohort Phase I clinical trial for the treatment of solid...

2014-01-27 08:27:54

Trial to evaluate ID-G100 in patients with Merkel cell carcinoma SEATTLE and SOUTH SAN FRANCISCO, Calif., Jan. 27, 2014 /PRNewswire/ -- Immune Design, a clinical-stage biotechnology company focused on the development of novel immune-based therapies for cancer and other chronic conditions, today announced treatment of the first patient in a Phase 1 clinical trial of ID-G100 in patients with Merkel cell carcinoma (MCC). (Logo: http://photos.prnewswire.com/prnh/20130926/SF87058LOGO)...

2012-05-09 21:36:44

Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus that, in animal studies, could be targeted to selectively kill the tumor cells. The treatment will soon be tested in patients. Merkel cell carcinoma (MCC), a skin cancer that is more common among seniors and those with weakened immune systems, could not be readily...

2009-09-24 07:17:30

The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus known to be associated with a rare skin cancer, known as Merkel cell carcinoma, according to a new study published online September 23 in the Journal of the National Cancer Institute. The majority of patients with Merkel cell carcinoma carry MCPyV, but little is known about the polyomavirus' prevalence in the general population and the association between circulating antibodies against MCPyV and the rare skin cancer. Denise...


Latest Merkel cell polyomavirus Reference Libraries

45_c8d4395f53eb6d3d4b08458e135e5ef0
2011-02-23 17:31:48

Polyomavirus is the sole genus of viruses within the family Polyomaviridae. Ludwik Gross discovered the first polyomavirus, Murine polyomavirus, in 1963. Many polyomaviruses infect birds and mammals and have been extensively studied as tumor viruses in humans and animals. Polyomaviruses are DNA-based, small, and icosahedral in shape. They can potentially cause tumors and often persist as latent infections in a host without causing disease. There are three major clades or...

45_16476fe85b6c94ca2cddefe0d4dea632
2011-02-17 16:45:25

Merkel cell polyomavirus (MCV or MCPyV), first discovered in January 2008, is one of seven human tumor viruses. It is suspected to cause most of Merkel cell carcinoma which is a rare, aggressive form of skin cancer. Around 80% of Merkel cell carcinoma tumors are found to be infected with MCV. It is found in respiratory secretions suggesting that it may be transmitted by a respiratory route. Usually the tumors with MCV viruses go through at least two mutations that render the virus...

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Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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