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Latest Messenger RNA Stories

2014-01-06 08:26:25

CAMBRIDGE, Mass., Jan. 6, 2014 /PRNewswire/ -- Moderna Therapeutics, the pioneer in developing messenger RNA (mRNA) Therapeutics(TM), a revolutionary new treatment modality to enable the in vivo production of therapeutic proteins, announced today that President and founding Chief Executive Officer Stephane Bancel will present a company overview at the 32(nd) Annual J.P. Morgan Healthcare Conference. Bancel will focus on the potential of Moderna's mRNA therapeutics to transform drug...

How Rare 'Words' In Bacterial Genes Boost Protein Production
2013-09-27 07:29:50

Wyss Institute for Biologically Inspired Engineering at Harvard Scientists routinely seek to reprogram bacteria to produce proteins for drugs, biofuels and more, but they have struggled to get those bugs to follow orders. But a hidden feature of the genetic code, it turns out, could get bugs with the program. The feature controls how much of the desired protein bacteria produce, a team from the Wyss Institute for Biologically Inspired Engineering at Harvard University reported in the...

2013-08-21 10:43:26

Researchers have long known that high levels of a specific protein in human cells are linked to tumor growth – but no one has fully understood how. Now, a groundbreaking discovery by UC Davis graduate student Kateryna Feoktistova and Assistant Professor Christopher Fraser illuminates the way that the protein, eukaryotic initiation factor 4E (eIF4E), acts upon cancer-promoting messenger RNA molecules. When translated, this type of mRNA can trigger the runaway cell replication that results...

2013-07-01 11:55:56

Synthetic biology technology could lead to new antibiotics, modified protein-generators Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube. Others have previously tried to synthesize ribosomes from their constituent parts, but the efforts have yielded poorly functional...

This Image May Lead To Better Antibiotics
2013-06-28 13:45:14

Lawrence Berkeley National Laboratory Berkeley Lab scientists create atomic-scale structure of ribosome attached to a molecule that controls its motion This may look like a tangle of squiggly lines, but you're actually looking at a molecular machine called a ribosome. Its job is to translate DNA sequences into proteins, the workhorse compounds that sustain you and all living things. The image is also a milestone. It's the first time the atom-by-atom structure of the ribosome has been...

2013-06-17 09:56:18

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates–a process commonly known as translation. While the general mechanism of translation has been understood for some time, protein synthesis can initiate by more than one mechanism. One of the least well understood mechanisms is known as cap-independent translation. Now, John Chaput and his colleagues at...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'