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Latest Messenger RNA Stories

2012-05-21 10:24:08

BRANFORD, Conn., May 21, 2012 /PRNewswire/ -- HistoRx, the leader in quantitative immunohistochemistry, announces the application of their proprietary AQUA technology to assessment of messenger RNA in tissue. AQUA technology enables robust quantification and standardization of protein in tissue specimens; this new work extends the platform's capabilities beyond protein expression analysis to quantification of nucleic acids. AQUA technology was invented to address the challenges of...

2012-05-18 02:18:32

Genetic discovery will revolutionize understanding of gene expression Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases. Now, researchers at Weill Cornell Medical College have made a discovery that once again forces us to rewrite our textbooks. This time, however, the findings...

2012-05-10 22:27:49

Max Planck researchers found over 2500 mRNA along dendrites and axons How do we build a memory in the brain? It is well known that for animals (and humans) new proteins are needed to establish long-term memories. During learning information is stored at the synapses, the junctions connecting nerve cells. Synapses also require new proteins in order to show changes in their strength (synaptic plasticity). Historically, scientists have focused on the cell body as the place where the required...

2012-05-09 21:29:37

Sanford-Burnham researchers develop a method called miR-TRAP, which allows scientists to better understand the roles microRNAs play in human development and disease Human cells are thought to produce thousands of different microRNAs (miRNAs)–small pieces of genetic material that help determine which genes are turned on or off at a given time. miRNAs are an important part of normal cellular function, but they can also contribute to human disease–some are elevated in certain...

2012-04-27 22:18:04

Novel regulatory molecules called mirror-microRNAs control multiple aspects of brain function Our genes control many aspects of who we are – from the colour of our hair to our vulnerability to certain diseases – but how are the genes, and consequently the proteins they make themselves controlled? Researchers have discovered a new group of molecules which control some of the fundamental processes behind memory function and may hold the key to developing new therapies for...

2012-02-29 14:09:28

It had long been assumed that the human sperm cell´s mission in life ended once it had transferred its freight of parental DNA to the egg. More recently however, other components of sperm have been implicated in fertilization, and perhaps even in subsequent embryonic development. In a new study appearing in the Proceedings of the Royal Society, Timothy Karr, a researcher at Arizona State University´s Biodesign Institute, along with colleagues from the Universities of Cambridge...

2012-02-01 07:00:00

MUNICH, Feb. 1, 2012 /PRNewswire/ -- Exosome Diagnostics GmbH, a subsidiary of Exosome Diagnostics, Inc., and the Department of Dermatology at the Ludwig Maximilian University (LMU) announces the awarding of a EUR one million grant from the German Federal Ministry for Education and Research (BMBF) to develop blood-based diagnostic tests from the stable RNA content accessible in plasma-derived exosomes. The grant will help fund development of exosome-based diagnostics technology to...

2012-01-19 14:55:49

Mutation in 1 copy of U2 snRNA lead to movement problems and early neuron death in mice A Jackson Laboratory research team led by Professor and Howard Hughes Medical Investigator Susan Ackerman, Ph.D., has discovered a defect in the RNA splicing process in neurons that may contribute to neurological disease. The researchers found that a mutation in just one of the many copies of a gene known as U2 snRNAs, which is involved in the intricate processing of protein-encoding RNAs, causes...

2012-01-12 07:00:00

MADISON, Wisconsin, January 12, 2012 /PRNewswire/ -- Hereditary hearing loss is the most common sensory disorder in humans. A German research team led by Ingo Kurth from the Institute of Human Genetics [http://www.humangenetik.uniklinikum-jena.de/Institut+f%C3%BCr+Humangenetik.html ] at the University Hospital Jena [http://www.med.uni-jena.de ], Germany, used a number of different methods, including Roche's NimbleGen Custom Sequence Capture 385K array to identify the gene...

2011-12-22 15:50:55

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered the first known mechanism by which cells control the survival of messenger RNA (mRNA) –arguably biology's most important molecule. The findings pertain to mRNAs that help regulate cell division and could therefore have implications for reversing cancer's out-of-control cell division. The research is described in today's online edition of the journal Cell. "The fate of the mRNA molecules we...