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Latest Messenger RNA Stories

2011-12-01 01:36:11

Researchers at the Hebrew University of Jerusalem and the University of Vienna have revealed for the first time a stress-induced machinery of protein synthesis that is involved in bringing about cell death in bacteria. Their work opens a new chapter in the understanding of protein synthesis under stress conditions, which are the conditions bacteria usually are faced with, both in humans and otherwise in nature, and could pave the way for the design of novel, new antibiotics that would help...

The Genetics Of High Blood Pressure
2011-11-09 09:20:02

Study co-authored by University of Leicester cardiovascular expert identifies key genetic mechanisms that help control blood pressure A researcher from the University of Leicester's Department of Cardiovascular Sciences has been involved in a ground-breaking study into the causes of high blood pressure. The study, published in the academic journal Hypertension, analyzed genetic material in human kidneys in a search for genes that might contribute to high blood pressure. The findings...

2011-10-16 21:35:01

Study illuminates the 'dark matter' of the genome Researchers at Columbia University Medical Center (CUMC) and two other institutions have uncovered a vast new gene regulatory network in mammalian cells that could explain genetic variability in cancer and other diseases. The studies appear in today's online edition of Cell. "The discovery of this regulatory network fills in a missing piece in the puzzle of cell regulation and allows us to identify genes never before associated with a...

2011-10-06 11:26:25

Researchers at Brown University and Women & Infants Hospital of Rhode Island have developed a way to extract information about gene expression from fertile human egg cells without hurting them. Expendable ℠polar bodies´ in the cells reflect much the same information as the eggs themselves, researchers have determined. Given the stakes of in vitro fertilization, prospective parents and their doctors need the best information they can get about the eggs they will extract,...

2011-09-19 18:40:00

In a new study, Chen-Yu Zhang's group at Nanjing university present a rather striking finding that plant miRNAs could make into the host blood and tissues via the route of food-intake. Moreover, once inside the host, they can elicit functions by regulating host "target" genes and thus regulate host physiology. MicroRNAs are a class of 19-24 nucleotide non-coding RNAs that do not code for proteins. MicroRNAs bind to target messenger RNAs to inhibit protein translation. In previous studies,...

2011-09-15 20:21:12

Scientists at the University of California, San Diego School of Medicine have uncovered a previously unknown fail-safe (compensatory) pathway that potentially protects the brain and other organs from genetic and environmental threats. The discovery could provide new ways to diminish the negative consequences of genetic mutations and environmental toxins that cause neurological diseases and other maladies. The findings are published in the Sept. 16 issue of the journal Molecular Cell....

2011-09-15 20:16:08

Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single event in a process called alternative splicing. Alternative splicing allows one gene to generate many different genetic messages and protein products. The researchers found that in genetic messages of a gene called FOXP1, the switch was active in embryonic stem cells...

2011-09-07 06:15:00

HOERSHOLM, Denmark and SAN DIEGO, Sept. 7, 2011 /PRNewswire/ -- Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, today announced advancements from the company's RNA-targeted research programs utilizing its proprietary Locked Nucleic Acid (LNA) Drug Platform. In addition to a presentation on the Company's microRNA-targeted drug miravirsen, a total of six abstracts/posters are being showcased...

2011-08-23 11:14:00

MANSFIELD, Mass., Aug. 23, 2011 /PRNewswire/ -- PrimeraDx today announced the launch of the ICEPlex® system, the only instrument on the market used for simultaneous detection and quantification of disparate target types, such as mRNA, miRNA, SNPs and DNA "We are excited to have launched the ICEPlex, a quantitative multiplex PCR platform," stated President and CEO Matthew McManus, MD, PhD. "No longer will users have to rely on semi-quantitative multiplex solutions. The...

2011-08-16 23:08:53

As part of a joint research effort with the University of Michigan, scientists from the Florida campus of The Scripps Research Institute have for the first time defined the structure of one of the cell's most basic engines, which is required for cell growth, as it assembles from its components. The study reveals a series of redundant mechanisms that assure production of these critical structures while avoiding any missteps that could lead to their destruction or to the production of incorrect...