Quantcast

Latest Messenger RNA Stories

2010-09-13 12:02:53

The findings could lead to new understanding of neurodegenerative diseases Scientists from The Scripps Research Institute have solved a long-standing mystery of how cells conduct "quality control" to eliminate the toxic effects of a certain kind of error in protein production. The findings may lead to a better understanding of a host of neurodegenerative diseases. The research was published in an advance, online issue of the journal Nature on September 12, 2010. "It is exciting because we are...

2010-09-08 15:29:00

IPSWICH, Mass., Sept. 9 /PRNewswire/ -- New England Biolabs (NEB) has expanded its line of reagents for sample preparation upstream of next generation sequencing with the introduction of NEBNext® mRNA Sample Prep Reagent Set 1 and Master Mix Set 1. These new products include enzymes, buffers and protocols for the conversion of purified mRNA to DNA, followed by library construction. The reagents are suitable for non-directional mRNA library preparation for...

2010-08-16 18:28:05

FINDINGS: Short pieces of RNA, called microRNAs, control protein production primarily by causing the proteins' RNA templates (known as messenger RNA or mRNA) to be disabled by the cell, according to Whitehead Institute scientists. RELEVANCE: Researchers have known that mammalian microRNAs control protein production by causing the mRNAs to degrade, but they have wondered how much additional effects microRNAs impart by jamming the process that translates mRNAs into proteins. These results from...

2010-08-16 15:33:33

In a discovery that has implications for developing treatments against cancer and potentially deadly viruses, researchers at SUNY Downstate Medical Center have discovered the function of proteins that can enhance the progression of certain viruses and cancer cells. Their findings were published in the journal Genes and Development. According to Tatyana Pestova, PhD, DSc, assistant professor of cell biology, and Christopher Hellen, DPhil, associate professor of cell biology, "The significance...

2010-07-28 19:20:23

Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady. In a study to be published July 29 in Nature, investigators used an animal model, the common fruit fly, to show that the mutation results...

8f647d76b1fdb82377f258a170d2f3d31
2010-06-13 07:36:15

Engineers turn a drawback "” the stickiness of gold nanoparticles "” into an advantage. Gold nanoparticles "” tiny spheres of gold just a few billionths of a meter in diameter "” have become useful tools in modern medicine. They've been incorporated into miniature drug-delivery systems to control blood clotting, and they're also the main components of a device, now in clinical trials, that is designed to burn away malignant tumors. However, one property of these...

2010-06-06 07:10:24

With the rapid and continuous advances in biotechnology, scientists are better able to see inside the nucleus of a cell to unlock the secrets of its genetic material. However, what happens outside of the nucleus has, in many ways, remained a mystery. Now, researchers with the National Institutes of Health are closer to understanding how activity outside of the nucleus determines a cell's behavior. They looked at mouse immune cells and examined the types, amount, and activity of microRNAs,...

a9ae9ef82642d17bde6bfc0a3b3c5a7f1
2010-03-22 06:45:00

Researchers unveil scientific results from siRNA Phase I clinical trial in cancer patients A California Institute of Technology (Caltech)-led team of researchers and clinicians has published the first proof that a targeted nanoparticle"”used as an experimental therapeutic and injected directly into a patient's bloodstream"”can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn off an important cancer gene using a mechanism known as RNA...

5788a15e2908a5fd7d5f9579955466951
2010-03-11 00:50:00

STANFORD, Calif. -- About four out of every 10 cells in the brain are so-called oligodendrocytes. These cells produce the all-important myelin that coats nerve tracts, ensuring fast, energy-efficient transmission of nerve impulses. Mixed among them are proliferating but not particularly proficient precursor cells that are destined to become oligodendrocytes when needed but, for now, remain suspended in an immature, relatively undifferentiated state somewhere between stem cell and adult...

bafe1b4581e6c0601aeb80301de350131
2010-02-16 11:05:46

One of the difficulties of fighting cancer is that drugs often hit other non-cancerous cells, causing patients to get sick. But what if researchers could sneak cancer-fighting particles into just the cancer cells? Researchers at the Georgia Institute of Technology and the Ovarian Cancer Institute are working on doing just that. In the online journal BMC Cancer they detail a method that uses hydrogels - less than 100 nanometers in size - to sneak a particular type of small interfering...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
Related