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Latest metabolic disease Stories

obesity
2014-07-20 10:34:28

Sanford-Burnham Medical Research Institute Study finds that the NBR1 protein plays a critical role in regulating obesity-induced inflammation that leads to metabolic disease A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a new signal that triggers the events leading to insulin resistance in obesity. The signal causes inflammation in adipose tissue and leads to metabolic disease. The study, published July 17 in Cell Metabolism,...

2014-05-02 00:21:47

SOUTH SAN FRANCISCO, Calif., May 2, 2014 /PRNewswire/ -- Second Genome announced today that it has entered into an agreement with Pfizer Inc. to conduct extensive microbiome research in a large observational study aimed at gaining new insights into obesity and metabolic disease. The goal of the study is to evaluate numerous clinical factors and the microbiome in a select cohort of approximately 900 individuals with varying metabolic phenotypes, in order to better understand the...

2012-08-16 01:12:54

The work may pave the way for new therapies for obesity and diabetes Working with a national team of researchers, a scientist from the Florida campus of The Scripps Research Institute has shown for the first time a link between low levels of a specific hormone and increased risk of metabolic disease in humans. The study, published online ahead of print in The Journal of Clinical Endocrinology & Metabolism, focuses on the hormone adropin, which was previously identified by Scripps...

2012-07-16 23:03:54

A recent study by researchers at the Beth Israel Deaconess Medical Center (BIDMC), published in the July 3 issue of Cell Metabolism, has identified the link between metabolic disease and cancer. Senior author Barbara Kahn, MD, a scientist at BIDMC and Professor of Medicine at Harvard Medical School, stated that “Maintaining normal body weight requires tight control of energy homeostasis, which necessitates a constant flow of metabolic input to the hypothalamus in the form of nutrients...

2010-07-22 15:31:44

A new study by Johns Hopkins researchers has found that insulin, the sugar-regulating hormone, is required for normal bone development and that it may provide a link between bone health and metabolic disease, such as diabetes. The study, headed by Thomas Clemens, Ph.D., the Lewis Cass Spencer Professor of Orthopaedic Surgery, and published online in the journal Cell, identified a unique communication between bone and pancreas cells through which insulin signaling in osteoblasts "” cells...

2010-05-25 05:00:00

SAN DIEGO, May 25 /PRNewswire/ -- aTyr announced today that John Mendlein, Ph. D., has joined their Board of Directors as Executive Chairman. The translation of aTyr's newly found class of proteins, resectins, into medicines of the future will benefit from Dr. Mendlein's experience in biologics, partnerships, and product strategy. Resectins may serve as potential replacement protein therapeutics or as targets for antagonists relevant to inflammation, blood disorders, and metabolic...

2005-07-22 18:00:00

SANTA CLARA, Calif. -- July 22, 2005 "“ Scientists at Galileo Pharmaceuticals, Inc. have demonstrated a direct relationship between inflammation and glucose levels. Through its recently established metabolic disease program, Galileo confirmed in preclinical models that inhibiting lipoxygenases, known mediators of inflammatory response, significantly lowers blood glucose levels in animal models of diabetes. "Metabolic disease is a health concern of near-epidemic proportions,...

2005-07-05 17:00:15

CAMBRIDGE, Mass., July 5, 2005 "“ During the last decade researchers have made a number of important discoveries about the molecular mechanisms regulating aging. This research has suggested the exciting prospect that the rate of aging can be manipulated and slowed, leading to longer human lifespan. A major peer-reviewed article in the current issue of Nature Reviews Drug Discovery describes the intimate links between these pathways of aging and those of metabolic disease, such as type 2...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'